Scientists expose COPD patients to ozone to uncover Pollution's hidden impact
NCT ID NCT04669743
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how ozone, a common air pollutant, affects immune cells in the lungs of people with COPD. Researchers will expose 72 participants (including healthy non-smokers, smokers without COPD, and COPD patients) to ozone in a controlled chamber and track changes in their lung immune cells. The goal is to understand why pollution triggers COPD flare-ups, which could lead to better prevention strategies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ozone exposure
- What this could lead to
- If successful, this could help explain why air pollution worsens COPD symptoms, pointing toward new ways to prevent flare-ups.
- What could go wrong
- This is an early observational study with no treatment being tested. Results may not lead to direct patient benefits or apply to real-world pollution scenarios.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for AIRWAY DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
San Francisco VA Medical Center
San Francisco, California, 94121, United States
-
University of California, San Francisco
San Francisco, California, 94122, United States
-
Zuckerberg San Francisco General Hospital and Trauma Center
San Francisco, California, 94110, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Smart breathing machines at home: a new way to predict COPD crises?
- Breathing easy? new X-Ray method may spot COPD decline early
- Blood test may curb antibiotic overuse in COPD attacks
- Could a common heart drug cut COPD hospitalizations?
- Can a new injection ease COPD and cut Flare-Ups?
- Smartphone and fitbit data may forecast COPD attacks