Scientists expose COPD patients to ozone to uncover Pollution's hidden impact
NCT ID NCT04669743
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how ozone, a common air pollutant, affects immune cells in the lungs of people with COPD. Researchers will expose 72 participants (including healthy non-smokers, smokers without COPD, and COPD patients) to ozone in a controlled chamber and track changes in their lung immune cells. The goal is to understand why pollution triggers COPD flare-ups, which could lead to better prevention strategies.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ozone exposure
What this could lead to
If successful, this could help explain why air pollution worsens COPD symptoms, pointing toward new ways to prevent flare-ups.
What could go wrong
This is an early observational study with no treatment being tested. Results may not lead to direct patient benefits or apply to real-world pollution scenarios.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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San Francisco VA Medical Center
San Francisco, California, 94121, United States
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University of California, San Francisco
San Francisco, California, 94122, United States
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Zuckerberg San Francisco General Hospital and Trauma Center
San Francisco, California, 94110, United States