New breathing tube strategy aims to prevent lung collapse in ventilated patients

NCT ID NCT05526053

Completed Knowledge-focused Sponsor: Althaia Xarxa Assistencial Universitària de Manresa Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two ways of taking patients off a mechanical ventilator to see which leads to more successful removals. One method used a standard breathing trial without extra pressure, while the other kept the lungs slightly inflated during the trial and removed the tube without suctioning. Over 1,700 adults on ventilators for more than 24 hours took part. The goal was to find out if preserving lung volume reduces breathing tube failure and lung collapse.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple change in how patients are taken off ventilators, reducing breathing tube failures and lung collapse.
What could go wrong: This is an early-stage comparison of two techniques, not a new drug or device. Results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pulmonary Atelectasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULMONARY COLLAPSE WEANING FAILURE

Contacts and locations

Locations

Althaia Xarxa Assistencial

Manresa, Bacelona, 08243, Spain

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