UROLITHIASIS
Clinical trials for UROLITHIASIS explained in plain language.
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Which kidney stone blaster works best? study compares three top methods.
Disease control CompletedThis study compared three procedures for removing hard kidney stones that are not in the lower part of the kidney: flexible ureteroscopy (FURS), shock wave lithotripsy (ESWL), and mini-percutaneous nephrolithotomy (Mini-PCNL). 300 adults with a single stone up to 2 cm were random…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Sound waves smash kidney stones without surgery
Disease control CompletedThis study tested a device called Break Wave™ that uses focused ultrasound waves to break kidney stones into tiny pieces that can pass naturally. 64 adults with upper urinary tract stones (4-10 mm) received the treatment. The goal was to see if the device is safe and effective at…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: SonoMotion • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New device aims to suck out kidney stones more safely
Disease control CompletedThis study tested a new tool called the CVAC System, a steerable catheter that helps remove kidney stones during a procedure called ureteroscopy. Thirty adults with kidney stones took part. The main goal was to see how safe the device is and how well it clears stones, measured by…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Calyxo, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:24 UTC
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Tiny Aircraft-Inspired scope could revolutionize kidney stone removal
Disease control CompletedThis study tested a new miniature endoscope called the 'Aircraft Nephroscope' for removing kidney stones. 216 patients underwent surgery with this device to see if it is safe and effective. The main goal was to check how many stones were completely removed and how many complicati…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: The First Affiliated Hospital of Guangzhou Medical University • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Vacuum cleaner for kidneys? new technique may suck out stone fragments better
Disease control CompletedThis study tested a new way to remove kidney stone pieces after laser treatment. Instead of using a tiny basket to grab each fragment, the SURE procedure gently vacuums them out. Researchers compared how many patients became completely stone-free with each method in 132 adults. T…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Calyxo, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:09 UTC
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New citrate cocktail may dissolve tough kidney stones without surgery
Disease control CompletedThis study tested a citrate mixture (citric acid, potassium bicarbonate, and sodium citrate) to dissolve coral-like urate kidney stones in 49 patients. The goal was to see if the treatment could shrink or eliminate stones, potentially avoiding surgery. Patients took a personalize…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Moscow State University of Medicine and Dentistry • Aim: Disease control
Last updated Jun 26, 2026 14:44 UTC
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AI-Powered Ultra-Low radiation CT could revolutionize kidney stone diagnosis
Diagnosis CompletedThis study tested whether an ultra-low-dose CT scan, combined with a deep-learning AI reconstruction, can accurately detect urinary tract stones. 62 adults with known or suspected kidney stones received both a standard low-dose CT and an additional ultra-low-dose scan (less than …
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Diagnosis
Last updated Jun 27, 2026 14:00 UTC
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Texts and gadgets aim to keep kidney stones away
Prevention CompletedThis study tested whether digital tools like a smart water bottle, a fitness watch, and text reminders could help people with a history of kidney stones drink more water as their doctor recommended. 216 adults who had a kidney stone in the past 5 years and drank less than 2 liter…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated Jun 26, 2026 18:19 UTC
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Nurse-Led lessons calm kidney stone patients before shock wave treatment
Symptom relief CompletedThis study tested whether a structured education session led by a nurse could lower anxiety and improve quality of life in 188 adults having their first shock wave lithotripsy for kidney stones. The education covered what to expect during the procedure, pain management, and recov…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: KTO Karatay University • Aim: Symptom relief
Last updated Jun 27, 2026 12:38 UTC
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Simple stress ball eases pain and anxiety during kidney stone procedure
Symptom relief CompletedThis study tested whether using a stress ball during a non-surgical kidney stone treatment (ESWL) can reduce pain and anxiety. 64 adults having their first ESWL session participated. The stress ball is a simple, cheap tool that distracts the mind. Researchers measured pain, anxie…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Mersin University • Aim: Symptom relief
Last updated Jun 27, 2026 12:33 UTC
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New laser may speed up kidney stone removal
Symptom relief CompletedThis study compared two FDA-approved lasers used to break up kidney stones during surgery: the newer SOLTIVE Thulium Fiber Laser and the standard Ho:YAG laser. About 100 adults with a single stone smaller than 2 cm took part. Researchers measured how well each laser cleared stone…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: University of Kansas Medical Center • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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New suction device may improve kidney stone removal
Symptom relief CompletedThis study tested two different tools used during surgery to remove kidney stones up to 20 mm. One is a traditional tube that lets fluid and stone pieces flow out, and the other is a newer tube that uses suction to actively pull out stone fragments. The goal was to see which tool…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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New study finds best method to zap kidney stones in kids
Symptom relief CompletedThis study looked at 180 children aged 6-12 with hard kidney stones (1-2 cm). It compared two procedures: mini-PCNL (a small back incision) and flexible ureteroscopy (a tube through the urinary tract). The goal was to see which method removes stones more completely and safely. Re…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC
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New study reveals best technique for kidney stone removal
Symptom relief CompletedThis study tested three different methods for removing kidney stones up to 2 centimeters in size. All methods use a flexible scope through the urinary tract, but one uses a traditional tube, another uses a tube with suction, and the third uses no tube at all. Researchers measured…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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Common prostate drugs ease kidney stone surgery, study finds
Symptom relief CompletedThis study looked at whether taking a type of medication called alpha-blockers (tamsulosin or silodosin) before a specific kidney stone surgery (RIRS) makes it easier for doctors to insert a needed tube and reduces damage to the tube that carries urine from the kidney to the blad…
Matched conditions: UROLITHIASIS
Sponsor: St. Luke's Clinical Hospital, Russia • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Skip the tube? study tests No-Catheter recovery after stone removal
Symptom relief CompletedThis study looked at whether leaving out the urinary catheter after ureteroscopic kidney stone surgery reduces pain and urgency. 180 adults aged 18-70 with normal kidney function took part. Researchers compared pain scores and urgency between those with and without a catheter to …
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Could a single pill before surgery cut opioid use after kidney stone treatment?
Symptom relief CompletedThis study tested whether giving a single dose of pregabalin (Lyrica) before ureteroscopy—a surgery for kidney stones that often leaves a temporary stent in the ureter—can reduce pain and the need for opioid painkillers afterward. 118 adults were randomly assigned to receive eith…
Matched conditions: UROLITHIASIS
Phase: PHASE2, PHASE3 • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated Jun 27, 2026 07:57 UTC
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Tiny study tests nerve block for kidney stone pain
Symptom relief CompletedThis study tested a procedure called an erector spinae plane block to see if it could help with pain from kidney stones. Only 5 people took part, all of whom had already received one pain medication in the emergency room. The results are very early and not enough to draw firm con…
Matched conditions: UROLITHIASIS
Phase: PHASE2 • Sponsor: University of Michigan • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Keyhole vs scope: which stone surgery wins?
Symptom relief CompletedThis study compared two common surgeries for removing large kidney stones stuck in the upper ureter: ureteroscopic lithotripsy (URS) and laparoscopic ureterolithotomy (LU). Fifty-six adults with a single stone between 10-20 mm were randomly assigned to one procedure. Researchers …
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Lahore General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Which tool is faster for inserting a breathing tube? new study compares two devices
Knowledge-focused CompletedThis completed study compared two devices used to place a breathing tube during kidney stone surgery: a videolaryngoscope and a VideoLMA. Researchers measured how long each took and how often they worked on the first try. The trial involved 100 adults and aimed to find which devi…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ela Erdem Hıdiroglu • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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App and bottle combo aims to flush away kidney stones
Knowledge-focused CompletedThis study tested a system called sipIT that uses a smart water bottle and phone app to track fluid intake and send reminders. The goal was to see if it helps kidney stone patients form a habit of drinking more fluids. 172 adults with a recent kidney stone diagnosis used the syst…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:37 UTC
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New study aims to take the guesswork out of kidney stone laser surgery
Knowledge-focused CompletedThis study looked at 61 adults with kidney stones to see if stone size and density could predict how much laser energy is needed during a procedure called thulium fiber laser lithotripsy. Researchers used CT scans before surgery to measure stone volume and density, then tracked t…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Bozok University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Kidney stone surgery bleeding risk may be lower than thought
Knowledge-focused CompletedThis study reviewed 500 patients who had a common kidney stone surgery (PCNL) done by one surgeon. The goal was to find out how often significant bleeding and blood transfusions actually happen. The results could help doctors give patients more accurate information about the risk…
Matched conditions: UROLITHIASIS
Sponsor: Elazıg Fethi Sekin Sehir Hastanesi • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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3D-CT outshines old formula for kidney stone stent prediction
Knowledge-focused CompletedThis study tested whether a 3D-CT scan can better predict if a patient with a 1-2 cm kidney stone will need a stent after shockwave treatment, compared to the usual formula. Fifty-six adults with a single stone were treated without a stent first, and their stone volume was measur…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Small study compares standard vs mini kidney stone surgery
Knowledge-focused CompletedThis completed trial compared two surgical procedures for removing kidney stones: standard PCNL and mini-PCNL. The study enrolled 18 adults with stones 10-20mm and measured blood loss, complications, and recovery time. The goal was to see if the smaller incision approach offers a…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC
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Breathing machine settings may change kidney stone surgery success
Knowledge-focused CompletedThis study looked at 70 adults having kidney stone surgery to see if the amount of air given by the breathing machine (tidal volume) affects how the surgery goes. Researchers compared low versus standard tidal volume settings to see if they changed surgery time, stone removal rat…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Tarik Emre Sener • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Less gas, same safety: new anesthesia method cuts drug use in kidney stone surgery
Knowledge-focused CompletedThis study tested two ways of giving anesthesia gas (sevoflurane) during kidney stone surgery. One method used a very low gas flow (minimal-flow), the other a slightly higher flow (low-flow). In 62 adults, the minimal-flow approach used less anesthesia drug while keeping patients…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC