UROLITHIASIS
Clinical trials for UROLITHIASIS explained in plain language.
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New citrate therapy shows promise for dissolving complex kidney stones
Disease control CompletedThis study tested a medication (citrate mixtures) to dissolve coral-like urate kidney stones in 49 patients. The goal was to see if the treatment could safely shrink or eliminate the stones without surgery. Researchers used CT scans to measure stone size and density, and checked …
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Moscow State University of Medicine and Dentistry • Aim: Disease control
Last updated May 17, 2026 03:59 UTC
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Sound waves zap kidney stones in new device trial
Disease control CompletedThis study tested a new device called Break Wave that uses sound waves to break kidney stones into tiny pieces. 64 people with upper urinary tract stones took part. The goal was to see if the device is safe and effective at breaking stones so they can pass naturally.
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: SonoMotion • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Kidney stone showdown: which procedure works best?
Disease control CompletedThis study compared three common procedures for removing medium-sized, hard kidney stones (not in the lower part of the kidney). 300 adults were randomly assigned to one of three groups: flexible ureteroscopy (FURS), shock wave lithotripsy (ESWL), or mini-percutaneous nephrolitho…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Kafrelsheikh University • Aim: Disease control
Last updated May 13, 2026 16:01 UTC
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New study finds best way to zap kidney stones in kids
Disease control CompletedThis study looked at 180 children aged 6 to 12 with hard kidney stones (1-2 cm) in the lower part of the kidney. It compared two surgeries: mini percutaneous nephrolithotomy (a small tube through the back) and flexible ureteroscopy (a scope through the urinary tract). The goal wa…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New tool zaps kidney stones with precision
Disease control CompletedThis study tested a new steerable catheter system called CVAC® to remove kidney stones. Thirty adults who needed stone removal surgery took part. The goal was to see if the device safely and effectively clears stones from the kidney.
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Calyxo, Inc. • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New study compares three kidney stone removal methods – which works best?
Disease control CompletedThis study looked at 90 adults with kidney stones up to 2 centimeters to see which surgical technique works best. Doctors compared three methods: using a traditional tube, a tube with suction, or no tube at all during a scope procedure. The goal was to find the safest and most ef…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Disease control
Last updated May 05, 2026 11:55 UTC
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Smart water bottles and apps help kidney stone patients stay hydrated
Prevention CompletedThis study tested whether using a smartwatch, a connected water bottle, and a mobile app can help people who have had kidney stones drink more water as their doctor recommends. 216 adults with a history of kidney stones and low urine volume took part. The goal was to see if these…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: University of Michigan • Aim: Prevention
Last updated May 17, 2026 03:53 UTC
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New suction technique may improve kidney stone removal
Symptom relief CompletedThis study tested a new way to remove kidney stone fragments after laser treatment, using a suction device called CVAC instead of the usual basket. About 132 adults with kidney stones took part. The goal was to see if the suction method leaves fewer stone pieces behind, which cou…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Calyxo, Inc. • Aim: Symptom relief
Last updated May 17, 2026 03:59 UTC
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Keyhole vs. scope: which stone surgery wins?
Symptom relief CompletedThis study compared two common surgeries for removing large upper ureteral stones (10-20 mm): ureteroscopic lithotripsy (URS), which uses a thin scope through the urinary tract to break the stone, and laparoscopic ureterolithotomy (LU), which uses small abdominal incisions to rem…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Lahore General Hospital • Aim: Symptom relief
Last updated May 17, 2026 03:53 UTC
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New suction tool may make kidney stone surgery safer and more effective
Symptom relief CompletedThis study tested two different devices used during surgery to remove kidney stones up to 20 mm. One is a traditional tube that lets fluid and stone fragments flow out passively, and the other is a newer tube that uses suction to actively pull out fragments and reduce pressure in…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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Knowledge is power: study shows patient education may ease anxiety during kidney stone treatment
Symptom relief CompletedThis study looked at whether structured education from a nurse could help patients feel less anxious and have a better quality of life when undergoing shock wave treatment for kidney stones. 188 adults having this treatment for the first time took part. The education aimed to red…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: KTO Karatay University • Aim: Symptom relief
Last updated May 14, 2026 12:06 UTC
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Tiny aircraft scope takes on kidney stones
Symptom relief CompletedThis study tested a new, smaller surgical tool called the "Aircraft Nephroscope" for removing kidney stones. 216 adults with kidney stones had surgery with this scope. The main goal was to see how well it removed stones and if it was safe. Results focused on stone-free rates and …
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: The First Affiliated Hospital of Guangzhou Medical University • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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Kidney stone surgery showdown: which procedure causes less bleeding?
Symptom relief CompletedThis study compared two surgical methods for removing kidney stones: standard PCNL and a smaller version called mini-PCNL. Researchers wanted to see which one causes less blood loss and leads to a quicker hospital discharge. The trial included 18 adults with stones between 10-20m…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated May 13, 2026 15:59 UTC
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Squeeze away the pain: stress ball eases kidney stone treatment
Symptom relief CompletedThis study tested whether using a stress ball during extracorporeal shock wave lithotripsy (ESWL) — a common, non-surgical treatment for kidney stones — can reduce pain and anxiety. Sixty-four adults having their first ESWL session were enrolled. Researchers measured pain levels,…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Mersin University • Aim: Symptom relief
Last updated May 11, 2026 20:50 UTC
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Pre-Surgery pills ease kidney stone procedure, reduce injury risk
Symptom relief CompletedThis study tested whether taking tamsulosin or silodosin before kidney stone surgery helps doctors insert a tube into the ureter more easily and reduces damage to the ureter. 140 adults with small kidney stones were involved. Results showed that those who took the medication had …
Matched conditions: UROLITHIASIS
Sponsor: St. Luke's Clinical Hospital, Russia • Aim: Symptom relief
Last updated May 11, 2026 20:49 UTC
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No catheter, less pain? new study on kidney stone surgery recovery
Symptom relief CompletedThis study looked at whether leaving out the urinary catheter after kidney stone surgery helps patients feel better. 180 adults who had the surgery were randomly assigned to either get a catheter or not. The main goal was to compare pain and urgency scores between the two groups.
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine • Aim: Symptom relief
Last updated May 11, 2026 20:39 UTC
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Kidney stone surgery bleeding risk: less than we thought?
Knowledge-focused CompletedThis study looked at 500 patients who had surgery for large kidney stones to find out how much bleeding actually occurs. The goal was to see if the real-world risk is lower than what is often reported in medical literature. The study only included patients treated by one surgeon …
Matched conditions: UROLITHIASIS
Sponsor: Elazıg Fethi Sekin Sehir Hastanesi • Aim: Knowledge-focused
Last updated May 17, 2026 04:00 UTC
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Breathing machine settings may change kidney stone surgery results
Knowledge-focused CompletedThis study looked at 70 adults having kidney stone surgery to see if the amount of air given by the breathing machine during anesthesia changes how the surgery goes. Patients were split into two groups based on whether they got low or standard air volume. Researchers measured sur…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Tarik Emre Sener • Aim: Knowledge-focused
Last updated May 17, 2026 03:58 UTC
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3D scans may predict stent need in kidney stone patients
Knowledge-focused CompletedThis study looked at 56 adults with a single kidney stone (1-2 cm) to see if a 3D CT scan could better predict the need for a stent before shockwave treatment. Researchers compared the 3D volume measurement to the traditional formula. The goal was to find a cutoff point that help…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Ain Shams University • Aim: Knowledge-focused
Last updated May 17, 2026 03:54 UTC
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New formula could predict laser power needed for kidney stone surgery
Knowledge-focused CompletedThis study enrolled 61 adults with kidney stones who were treated with a special laser (Thulium Fiber Laser) during a scope procedure. Researchers used CT scans before surgery to measure stone size, number, and hardness. They then analyzed how much laser energy was actually used …
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Bozok University • Aim: Knowledge-focused
Last updated May 15, 2026 11:55 UTC
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Kidney stone study uncovers secrets of drinking more water
Knowledge-focused CompletedThis study looked at how a 3-month program using a smart water bottle and phone app helps people who have had kidney stones drink more fluids. Researchers wanted to understand what makes people stick with healthy habits. 172 adults with a past kidney stone diagnosis took part. Th…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: University of Michigan • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Less anesthesia, same safety: new study on kidney stone surgery
Knowledge-focused CompletedThis study looked at two ways of giving anesthesia during kidney stone surgery. 62 adults were split into two groups: one got a very low gas flow (minimal-flow) and the other a slightly higher flow (low-flow). The main goal was to see how much anesthesia medicine was used. The st…
Matched conditions: UROLITHIASIS
Phase: NA • Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital • Aim: Knowledge-focused
Last updated May 11, 2026 20:47 UTC