ULCERATIVE COLITIS (UC)

This study looks at whether using just one medication (infliximab) under the skin works as well as using it together with another immune-suppressing drug for people with Crohn's disease or ulcerative colitis. About 420 adults who have already started infliximab will be followed f…

This early-stage trial tests a new drug called ALTB-268, a monoclonal antibody, in 24 healthy volunteers. The main goal is to check safety and how the body processes the drug. If it passes safety checks, it may later be tested in people with ulcerative colitis to see if it can co…

This phase 3 study tests whether risankizumab, an injected drug, can safely maintain remission in people with ulcerative colitis who already improved with the same drug. Over 1,200 participants will receive either risankizumab or a placebo for 52 weeks, with an option to continue…

This study tests the long-term safety and effectiveness of upadacitinib (RINVOQ) in about 950 people with ulcerative colitis who didn't respond well to earlier treatment. Participants take the drug or a placebo orally. The goal is to see if it can control the disease over time wi…

This study looks at whether adding CurQD, a mix of curcumin and QingDai, helps people with active ulcerative colitis who are already taking vedolizumab. Researchers will review records from 400 patients to see if the supplement helps them stay on vedolizumab longer and improves s…

This study looks at whether two blood markers, zonulin and LBP, can help detect liver damage in people with both ulcerative colitis (UC) and fatty liver disease. Researchers will measure these markers and use a special ultrasound to check liver stiffness in 100 adults with UC who…

This pilot study tests whether daily, at-home stimulation of a nerve in the ear can change brain activity in people with inflammatory bowel disease (IBD) who are in remission. Fifteen adults with Crohn's disease or ulcerative colitis will use a small device for 28 days and underg…

This study looks at how diet affects inflammation in people with Crohn's disease or ulcerative colitis (IBD). About 140 participants will either follow a Nordic-based test diet for six weeks or use a digital information tool. Researchers want to see if these approaches can reduce…

This study looks back at medical records of 120 adults with Crohn's disease or ulcerative colitis who switched from intravenous to subcutaneous (under-the-skin) vedolizumab. Researchers want to see what dosing patterns doctors used and whether patients achieved remission. No new …

This study aims to understand how inflammatory bowel disease (IBD) affects patients' quality of life. Researchers will survey 385 adults with Crohn's disease or ulcerative colitis about their symptoms, emotional well-being, and social support. The goal is to identify factors that…

This study is collecting health information from 2,000 people with Crohn's disease or ulcerative colitis across three hospitals in South Korea. Researchers aim to build computer models that can predict how each patient will respond to different treatments. No new drugs are being …