ULCERATIVE COLITIS (UC)

This study looked back at medical records to see if using the drug upadacitinib as the first major treatment for a severe flare of ulcerative colitis works better and is safer than using it only after other treatments have failed. Researchers analyzed data from 81 patients to com…

This study tested an investigational drug called IBI112 for people with moderate to severe ulcerative colitis, a chronic inflammatory bowel disease. About 150 participants received either the drug or a placebo to see if it could help achieve and maintain clinical remission over a…

This study followed 150 patients with inflammatory bowel disease (including Crohn's disease and ulcerative colitis) who received Vedolizumab treatment as part of their regular medical care. Researchers tracked how well the treatment worked and monitored for side effects over one …

This study tested whether four free, existing self-help resources could help adults with moderate-to-severe Crohn's disease or ulcerative colitis feel more in control and reduce their disability. Over 800 participants were randomly assigned different combinations of a book, a sma…

This study tested a special 15-day diet high in fiber, fermented foods, and berries to see how it changes gut bacteria and is tolerated by people. It involved 36 healthy adults and adults with inactive ulcerative colitis. Researchers collected stool, blood, and survey data to lea…

This study aimed to understand if variations in a specific gene (IL-7R) are linked to a person's risk of developing ulcerative colitis. Researchers also wanted to see if these gene variations could predict how well patients respond to a standard medication called vedolizumab. The…

This study aimed to see if two simple scores calculated from common blood tests (CALLY and HALP) could help doctors better understand and track flare-ups in people with ulcerative colitis. Researchers looked at 100 patients under 18 years old to check if changes in these scores m…

This study looked back at the medical records of 159 people with ulcerative colitis (UC) who were on newer, advanced medications. Researchers wanted to see if finding microscopic inflammation in colon tissue biopsies, even when the colon looks mostly okay during a scope exam, cou…