ULCERATIVE COLITIS (UC)

This study followed 150 people with inflammatory bowel disease (ulcerative colitis or Crohn's disease) who received VedAryo® (vedolizumab) to see if it is effective and safe. The main goal was to check if symptoms improved after 52 weeks. Since IBD is a chronic condition requirin…

This study tested an experimental drug called IBI112 in 150 people with moderate to severe ulcerative colitis, a chronic bowel disease causing inflammation and ulcers. The goal was to see if IBI112 could help patients achieve remission (no symptoms) after 12 weeks of treatment. P…

This study looked at 81 people with severe ulcerative colitis to see if starting upadacitinib early works better than using it after other treatments fail. Researchers checked remission rates and safety over 12 weeks. The goal is to help doctors choose the best timing for this me…

This study tested a 15-day diet rich in high-fiber foods, fermented foods, and berries in 36 healthy adults and adults with inactive (quiescent) ulcerative colitis. Participants provided blood, stool, and urine samples, and completed questionnaires about symptoms and quality of l…

This completed study tested whether four free self-help resources—a book, a smartphone app, a helpline, and a peer mentor—can help adults with Crohn's disease or ulcerative colitis feel more in control and reduce disability. Over 800 adults with moderate-to-severe IBD-related dis…

This study looked at 898 people to see if differences in the IL-7R gene are linked to getting ulcerative colitis (UC) and how well patients respond to the drug vedolizumab. Researchers compared UC patients with healthy volunteers to understand genetic risk factors. The goal is to…

This study looked at 159 people with ulcerative colitis who started a new advanced treatment. Researchers wanted to see if tiny signs of inflammation found in biopsies (called histologic activity) could predict future problems like hospital stays or surgery, even when the colon l…

This study examined how differences in the BAFF gene might influence the risk of developing ulcerative colitis and how well patients respond to the drug vedolizumab. Researchers analyzed genetic samples from 841 people with ulcerative colitis. The goal was to better understand th…

This study looked at 366 adults referred to hospitals with suspected inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. The goal was to find simple, non-invasive markers that could help doctors diagnose IBD more accurately and predict which patien…

This study looked at 100 people with ulcerative colitis to see if two blood-based scores (CALLY and HAALP) can help doctors tell when the disease is active. The goal was to find a simpler way to measure inflammation without invasive tests. The results may help improve monitoring …