Hidden clues in gut tissue may predict ulcerative colitis Flare-Ups

NCT ID NCT07188727

Completed Knowledge-focused Sponsor: IRCCS San Raffaele Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at 159 people with ulcerative colitis who started a new advanced therapy. Researchers examined tissue samples from the colon to see if microscopic signs of inflammation could predict future problems like hospital stays or surgery. The goal is to help doctors decide whether to change treatment earlier, even when the colon looks only mildly inflamed during a scope.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors decide when to adjust treatment for ulcerative colitis patients with mild inflammation, potentially preventing worse outcomes.
What could go wrong: This is a small, retrospective study that only looks back at past data, so it cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ULCERATIVE COLITIS (UC)

Contacts and locations

Locations

IRCCS San Raffaele Hospital

Milan, MI, 20132, Italy

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