Gene clues could personalize ulcerative colitis treatment
NCT ID NCT07398586
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study examined whether differences in the IL-7 receptor gene are linked to the risk of developing ulcerative colitis and how well patients respond to the drug vedolizumab. Researchers enrolled 898 people, including those with UC and healthy controls, and analyzed their genetic profiles. The goal is to understand if genetic testing could one day help tailor treatment decisions for UC patients.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
vedolizumab
What this could lead to
If successful, this could help doctors predict which ulcerative colitis patients will respond best to vedolizumab, leading to more personalized treatment.
What could go wrong
This is an observational genetic analysis, not a treatment trial. The findings may not change clinical practice and need further validation.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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the Second Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, China