Simple blood test may spot hidden liver trouble in colitis patients

NCT ID NCT07662902

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: University Hospital Dubrava Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether two blood markers, zonulin and LBP, can help detect liver damage in people with both ulcerative colitis (UC) and fatty liver disease. Researchers will measure these markers and use a special ultrasound to check liver stiffness in 100 adults with UC who are in remission. The goal is to see if these markers could be used to identify advanced liver problems without needing a biopsy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a simple blood test to detect serious liver damage in people with ulcerative colitis and fatty liver disease.
What could go wrong: This is an early observational study with only 100 participants. It only looks for a link, not a treatment, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alcoholic fatty liver disease fatty liver disease metabolic dysfunction-associated steatotic liver disease ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTESTINAL PERMEABILITY STEATOTIC LIVER DISEASE ULCERATIVE COLITIS (UC)

Contacts and locations

Locations

University Hospital Dubrava

Zagreb, 10000, Croatia

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