New antibody ALTB-268 enters human testing for ulcerative colitis

NCT ID NCT07350577

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a new drug called ALTB-268, a monoclonal antibody, in 24 healthy volunteers. The main goal is to check safety and how the body processes the drug. If it passes safety checks, it may later be tested in people with ulcerative colitis to see if it can control the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ALTB-268 (a monoclonal antibody)

What this could lead to

If successful, this could lead to a new treatment option for ulcerative colitis, helping control the disease and reduce symptoms.

What could go wrong

This is a very early Phase 1 trial in only 24 healthy people, not patients. It only tests safety and dosing, not whether it works for UC. Many early-stage drugs fail to show benefit later.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Syneos Health Clinical Research Services, LLC

    Miami, Florida, 33136, United States