TYPE2DIABETES

This study tests whether a continuous glucose monitor (CGM) paired with a coaching app helps pregnant women with type 2 diabetes achieve better blood sugar control compared to standard care. Participants use a Dexcom G7 CGM sensor and receive guidance through a mobile app and car…

This study tests a device called ReCET that delivers gentle electric pulses to the first part of the small intestine. The goal is to trigger cell regeneration and improve blood sugar control in people with type 2 diabetes who are not on insulin. Participants are randomly assigned…

This study tests whether a supplement called NMN can improve kidney health in people with type 2 diabetes and diabetic kidney disease. About 156 adults will take either NMN or a placebo twice daily for 6 months. The main goal is to see if NMN reduces protein in the urine, a key s…

This study compares two common diabetes drug classes—SGLT2 inhibitors and GLP-1 receptor agonists—to see which better prevents heart attacks, strokes, kidney failure, and death in 6,000 people with type 2 diabetes and heart disease or high risk. Participants are randomly assigned…

This study tests whether a low-fat vegan diet and nutrition classes can improve health and lower medical costs for people with type 2 diabetes. Seven hundred Blue Cross Blue Shield subscribers will follow the diet for 16 weeks. Researchers will measure changes in weight, blood su…

This study tests whether a 6-month program of problem-solving training, community health worker support, and exercise coaching at a YMCA can improve fitness and heart health in 210 adults with type 2 diabetes, obesity, and low income. Participants are compared to those who receiv…

This study helps older adults with type 2 diabetes talk to their doctors about switching from sulfonylurea drugs, which can cause dangerous low blood sugar and heart problems, to newer, safer options. About 220 participants will get either a simple question sheet to guide their n…

This study looks at whether doing a diabetes test right after giving birth (instead of waiting 4-12 weeks) helps more women get screened for type 2 diabetes after having gestational diabetes. It also asks women about their views on heart-health programs after pregnancy. About 104…

This study tests whether giving adults at risk for type 2 diabetes free fresh fruits and vegetables, along with a proven lifestyle program, can help them lower blood sugar and lose weight. One hundred adults with prediabetes will either get the standard diabetes prevention progra…

This study tests whether dialectical behavioral therapy (DBT), a type of talk therapy that teaches mindfulness and emotional skills, can help teens with obesity improve their quality of life and manage weight. About 90 teens aged 14-17 who show signs of depression and are at risk…

This study looks at whether a 12-week home-based strength training program, supported by technology and telehealth, is practical for 20 adults aged 55-80 with type 2 diabetes and mild cognitive impairment. Participants will start with supervised sessions and gradually exercise on…

This early-stage study tests whether taking vitamin B1 (thiamine) daily for three months can improve brain function and repair the blood-brain barrier in adults with type 2 diabetes. Researchers will use brain scans, memory tests, and blood markers to compare results between the …

This study tests whether a 6-week program of non-weight bearing exercise can help diabetic foot ulcers heal faster than standard wound care alone. Forty adults with type 2 diabetes and a foot ulcer will be randomly assigned to exercise plus standard care or standard care only. Re…

This study tests whether giving doctors a geriatric assessment—a quick check of frailty and function—helps them set safer blood sugar goals for patients aged 60+ with type 2 diabetes. 220 participants will be randomly assigned to usual care or to have their doctor receive the ass…

This study looks at how cutting calories affects the way the liver processes amino acids, sugars, and fats in people with type 2 diabetes. Researchers want to see if weight loss helps the liver respond better to a hormone called glucagon. About 20 adults with type 2 diabetes and …

This study looks at why diabetes can damage the heart even without clogged arteries. Researchers will examine heart tissue and use advanced imaging in 500 adults with heart failure, with or without type 2 diabetes. The goal is to find early warning signs and new treatment targets…

This study follows 35 people with severe obesity who are having mini-gastric bypass surgery. Researchers want to see how the surgery changes body composition and improves related health issues like type 2 diabetes, sleep apnea, high blood pressure, and fatty liver disease. The go…

This study looks at how SGLT2 inhibitors, a type of diabetes medicine, change energy levels in the heart and muscles. Researchers will measure key energy molecules in 71 adults with type 2 diabetes and heart failure. The goal is to understand how these drugs work, not to test a n…