TYPE2DIABETES

This study tests whether a supplement called NMN, which boosts a natural cell chemical called NAD, can improve kidney health in people with type 2 diabetes and early kidney disease. About 156 adults will take either NMN or a placebo twice daily for 6 months. The main goal is to s…

This study tests a 6-month program that combines exercise training, problem-solving help, and community health worker support for 210 adults with type 2 diabetes, obesity, and early heart problems. Participants must have low income and live in Baltimore or Washington County, Mary…

This study tests whether teaching people with type 2 diabetes how to follow a plant-based diet can improve their health and reduce medical costs. About 700 Blue Cross Blue Shield subscribers will attend weekly online classes for 16 weeks. Researchers will track weight, blood suga…

This study aims to find out which of two common diabetes medications—SGLT2 inhibitors or GLP-1 receptor agonists—is better at preventing serious heart and kidney events in people with type 2 diabetes. About 6,000 adults with diabetes and heart disease or high risk will be randoml…

This study tests if Dialectical Behavioral Therapy (DBT), which focuses on emotions and mindfulness, can help teens aged 14-17 with obesity improve their quality of life and manage weight to prevent type 2 diabetes. Participants will be randomly assigned to weekly group sessions …

This study looks at whether a 6-week program of non-weight bearing exercise (like seated leg movements) can help diabetic foot ulcers heal faster than standard wound care alone. Researchers will measure blood flow and metabolism changes. The trial involves 40 adults with type 2 d…

This study tests whether a 12-week home-based strength training program, supported by technology and telehealth, is practical for adults aged 55-80 with type 2 diabetes and mild cognitive impairment. Researchers will measure how many people complete the program and how often they…

This study tests whether taking vitamin B1 (thiamine) capsules can repair the blood-brain barrier and improve thinking and mood in adults with type 2 diabetes. About 52 participants will have brain scans, memory tests, and blood work at UCLA over two visits, three months apart. T…

This study looks at how diabetes changes the way heart cells use energy, which may lead to heart failure. Researchers will examine heart tissue and use imaging tests in 500 adults with heart failure, with or without type 2 diabetes. The goal is to better understand the disease an…

This study focuses on older adults with type 2 diabetes who are taking sulfonylurea medications, which can cause dangerous low blood sugar and other health risks. Researchers will give some patients a simple question sheet to help them talk with their doctor about switching to ne…

This study tests whether screening for diabetes right after giving birth (before leaving the hospital) is better than the usual 4-12 week wait. It also asks 104 women who had gestational diabetes about their views on heart health programs and what makes it easier or harder to joi…

This study looks at how a common diabetes medication (SGLT2 inhibitor) changes energy levels in the heart muscle. Researchers will measure key energy molecules in the heart before and after treatment. The goal is to understand if this drug helps the heart work better in people wi…

This study follows 35 people with severe obesity who are having mini-gastric bypass surgery as part of their routine care. Researchers want to see how the surgery helps improve related health problems like type 2 diabetes, sleep apnea, high blood pressure, and fatty liver disease…

This study looks at whether giving doctors a special geriatric assessment for their elderly patients with type 2 diabetes leads to better treatment decisions. About 220 people aged 60 and older will be randomly assigned to usual care or to have their doctor receive the assessment…