THORACOABDOMINAL AORTIC ANEURYSM

This study looks at how safe and effective custom-made stents are for treating complex bulges or tears in the main artery (aorta). About 760 people with large or fast-growing aneurysms will receive these special stents. Researchers will track deaths, major complications like hear…

This study tests whether specially modified grafts can safely repair complex aortic aneurysms in patients who are too high-risk for standard surgery. About 220 participants with abdominal or thoracoabdominal aneurysms or aortic dissections will receive a physician-modified endova…

This study tests a new way to repair complex aortic aneurysms (bulging blood vessels) using stents placed through small incisions, avoiding major open surgery. The procedure uses off-the-shelf devices to rebuild branches that supply vital organs. Researchers will check safety and…

This study is testing a stent device (TAMBE) to treat large bulges in the main artery of the chest and belly (thoracoabdominal aortic aneurysm). About 100 people will get the device, and doctors will check if it works safely and stays open. The goal is to control the aneurysm, no…

This study tests three custom-designed stents for people with complex aortic aneurysms that standard devices can't treat. The goal is to see if these stents reduce hospital stays, lung problems, and death. About 410 participants will be enrolled at one center.

This study tests a less invasive procedure to treat large aneurysms in the aorta (the main artery from the heart). Doctors place a stent-graft inside the aneurysm to seal it off and prevent rupture. The study includes up to 250 adults with aneurysms at least 5.5 cm wide (in women…

This study tests a doctor-modified stent graft to repair complex aortic aneurysms in patients who cannot use standard FDA-approved devices. About 40 high-risk adults will receive the custom graft and be followed for five years to check safety and success. The goal is to prevent a…

This study compares two ways to treat complex aortic aneurysms (a bulging blood vessel in the belly). One method uses a custom-made stent-graft, and the other uses a stent-graft shaped with the help of a 3D-printed model of the patient's aorta. The goal is to see which approach l…

This study looks at how safe and effective custom-made stents are for treating certain types of aortic aneurysms (bulges in the main artery). About 50 people who are too high-risk for traditional open surgery will receive these stents. Researchers will track serious complications…

This study compares two ways of using a heart-lung machine during open surgery for a thoracoabdominal aortic aneurysm (a bulge in the main artery). 236 adults from 4 hospitals in China will be randomly assigned to one of two bypass methods. The goal is to see which technique lead…

This study looks at whether a low dose of ketamine can help reduce the amount of strong painkillers (opioids) needed after a type of aortic repair surgery called TEVAR. About 30 adults having this surgery will receive either ketamine or a placebo, and their pain levels and opioid…