Ketamine may cut opioid use after major aortic surgery

NCT ID NCT04600089

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether a low dose of ketamine can reduce the amount of strong painkillers (opioids) needed and improve pain control in people recovering from thoracic endovascular aortic repair (TEVAR). About 30 adults scheduled for this surgery will receive either ketamine or a placebo alongside standard care. The goal is to see if ketamine can safely spare opioid use while managing pain effectively.

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Conditions

The condition(s) this trial relates to.

aortic aneurysm Aortic Aneurysm, Thoracoabdominal Pain, Postoperative spinal cord ischemia thoracic aortic aneurysm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Kentucky Medical Center

    RECRUITING

    Lexington, Kentucky, 40536, United States

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