SUBSTANCE USE DISORDER (SUD)

This study looks at whether adding proven addiction treatments—medication and therapy—to the VA's housing program helps homeless veterans with substance use disorders stay housed and recover. About 8,000 veterans will take part across multiple VA sites. The goal is to see if thes…

This study tests a program called TBI-RECOVER that screens for brain injury and related challenges in people receiving treatment for substance use disorder. The goal is to see if this program helps patients stay in treatment longer and feel better. About 900 patients and their pr…

This study tests if a safe dye (fluorescein sodium) added to a drink can prove a urine sample is authentic. 114 adults with substance use disorder will drink either dyed or plain Gatorade, then provide a urine sample 15 minutes later. Researchers will check for the dye using a sp…

This study looks at whether Written Exposure Therapy (WET), a short writing treatment for PTSD, can help people who also have substance use disorder (SUD) while they are in residential treatment. About 108 participants will either do WET or neutral writing sessions, plus their us…

This study tests a new program that combines addiction treatment with personalized job coaching to help people find work. About 100 adults with substance use disorders who are unemployed will be randomly assigned to either the new program or standard employment services. Research…

This study will test two new services at a large Chicago health clinic: routine substance use screening for all patients, and a program that asks people to refer friends or partners who might need HIV or addiction support. The goal is to see if these methods help more people lear…

This study looks at whether a special job training program helps people with substance use disorder recover better than standard employment services. About 50 adults involved in the justice system will take part. Researchers will measure changes in social connections, personal re…

This study tests a new program for adults in prison who have both ADHD and substance use disorder. The program includes workshops and team coordination to improve care and quality of life. Researchers will check if the program is acceptable and helpful by interviewing participant…

This study looks at how mood, behavior, and brain activity change in young adults (ages 18-21) who use cannabis. Researchers will use brain scans and questionnaires to understand why some people respond differently to the same drug. The goal is to learn more about individual diff…

This study will test a psychoeducation program based on cognitive behavioral therapy for 44 adults with substance use disorder. The program aims to reduce feelings of social exclusion and hopelessness, and improve skills to cope with relapse. Participants will be taught practical…

This study looks at how communities can better connect people with substance use disorders to support services instead of arresting them. Researchers will test two different community engagement approaches across 20 towns in five states. About 1,620 staff members will take part, …