STAGE IVB PROSTATE CANCER AJCC V8
Clinical trials for STAGE IVB PROSTATE CANCER AJCC V8 explained in plain language.
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Targeted drug combo aims to halt advanced prostate cancer in select patients
Disease control OngoingThis study is testing a combination of two drugs, niraparib/abiraterone and prednisone, in men with advanced prostate cancer that has spread and has stopped responding to standard hormone-blocking treatments. The treatment is specifically for patients whose cancer has a particula…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New drug combo tested to keep advanced prostate cancer in check
Disease control OngoingThis study is testing a combination of three drugs (apalutamide, abiraterone acetate, and prednisone) for men with advanced prostate cancer that has spread and is still sensitive to hormone-blocking therapy. The goal is to see if this combination, given after standard chemotherap…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: OHSU Knight Cancer Institute • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New drug combo tested for Tough-to-Treat advanced cancers
Disease control OngoingThis early-stage study is testing a new combination of two drugs, AZD8186 and docetaxel, for patients with advanced solid tumors that have specific genetic changes (PTEN or PIK3CB mutations). The main goals are to find the safest and most effective dose and to understand the side…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New drug trial targets Tough-to-Treat prostate cancer with specific gene flaw
Disease control OngoingThis study is testing an experimental drug called M1774 for men with advanced prostate cancer that has a specific genetic change (SPOP mutation) and has stopped responding to standard treatments. The goal is to see if M1774 can shrink or stop the growth of the cancer. About 20 pa…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:41 UTC
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New Two-Drug attack on tough, spreading cancers
Disease control OngoingThis early-stage study is testing a new combination of two drugs, DS3201 and ipilimumab, for people with advanced prostate, bladder, or kidney cancer that has spread. The main goals are to find the safest dose and understand the side effects. Researchers hope the drug combo will …
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New Two-Pronged attack on advanced prostate cancer
Disease control OngoingThis study is testing a combination of two drugs, olaparib and radium-223, for men with advanced prostate cancer that has spread to the bones and is no longer responding to standard hormone therapy. The goal is to find the safest dose and see if the combination can slow the cance…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New drug combo tested to control aggressive prostate cancer spread
Disease control OngoingThis study is testing whether a combination of three drugs can help control prostate cancer that has spread to other parts of the body. Researchers want to see if they can predict which patients will respond best to this treatment by analyzing tumor characteristics. The trial inv…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 24, 2026 12:01 UTC
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New immune therapy cocktail tested in fight against advanced cancers
Disease control OngoingThis study is testing the safety and effectiveness of avelumab, an immunotherapy drug, when given in combination with other immune-boosting drugs and sometimes radiation. It is for patients with advanced solid tumors that have spread and who have run out of standard treatment opt…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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New drug duo aims to outsmart advanced prostate cancer
Disease control OngoingThis study is testing if adding a drug called rucaparib to standard treatment (enzalutamide) works better for men whose prostate cancer has spread and stopped responding to hormone therapy. The goal is to see if the combination helps patients live longer or keeps their cancer fro…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Precision strike: new combo therapy aims to control spreading prostate cancer
Disease control OngoingThis study is testing a two-part treatment for prostate cancer that has returned and spread to a few other areas of the body. Patients receive hormone-blocking drugs for six months, combined with highly targeted radiation to the specific tumors. The goal is to see if this combine…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Jonsson Comprehensive Cancer Center • Aim: Disease control
Last updated Mar 18, 2026 18:25 UTC
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Smart scans aim to target deadly prostate cancer spread
Disease control OngoingThis study is testing whether a special type of imaging scan (PSMA PET) can help doctors better select patients for a targeted radiation treatment called Ra-223. The treatment is for men whose prostate cancer has become resistant to hormone therapy and has spread to their bones. …
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Mar 16, 2026 15:27 UTC
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Could prostate cancer patients take a break from harsh hormone drugs?
Disease control OngoingThis study is testing whether men with advanced prostate cancer that has spread can safely take a break from hormone-blocking medications when their cancer responds exceptionally well to treatment. The trial involves 79 men who have been on strong hormone therapy for 18-24 months…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 13, 2026 15:05 UTC
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New scan aims to sharpen prostate cancer detection
Diagnosis OngoingThis study is testing a new type of PET scan called 68Ga-PSMA-11 to see if it can better find and track prostate cancer. It enrolled 141 men with different stages of prostate cancer to see if this scan changes how doctors plan their treatment. The goal is to improve how doctors m…
Matched conditions: STAGE IVB PROSTATE CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Diagnosis
Last updated Mar 30, 2026 14:34 UTC