New trial aims to cut side effects of radiation for recurrent prostate cancer
NCT ID NCT04190446
First seen Nov 19, 2025 · Last updated Jun 22, 2026 · Updated 31 times
Summary
This phase II trial tests two types of radiation therapy (proton beam or IMRT) given in fewer, larger doses for men whose prostate cancer has returned or spread to a few spots after initial treatment. The main goal is to see if this shorter course causes fewer serious side effects in the gut and urinary tract. About 84 men will take part, and the study is actively recruiting.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
radiation therapy (proton beam or intensity-modulated radiation therapy)
What this could lead to
If successful, this could offer a shorter, safer radiation option for men with recurrent prostate cancer that has spread to a few sites.
What could go wrong
This is a small, early-phase trial (84 people) focused on side effects, not on curing the cancer. It may not lead to better outcomes or be widely applicable.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.