New trial aims to cut side effects of radiation for recurrent prostate cancer
NCT ID NCT04190446
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase II trial tests two types of radiation therapy (proton beam or IMRT) given in fewer, larger doses for men whose prostate cancer has returned or spread to a few spots after initial treatment. The main goal is to see if this shorter course causes fewer serious side effects in the gut and urinary tract. About 84 men will take part, and the study is actively recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- radiation therapy (proton beam or intensity-modulated radiation therapy)
- What this could lead to
- If successful, this could offer a shorter, safer radiation option for men with recurrent prostate cancer that has spread to a few sites.
- What could go wrong
- This is a small, early-phase trial (84 people) focused on side effects, not on curing the cancer. It may not lead to better outcomes or be widely applicable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can surgery boost control of spread prostate cancer?
- Can a better scan sharpen radiation for prostate cancer?
- Hormone therapy showdown: can an oral pill beat the shot for prostate cancer patients?
- Can a new drug tame metastatic prostate cancer? a phase 1 trial aims to find out
- Can tracking tumor movement during radiation make treatment more precise?
- Can a tracer that hunts unstable iron light up hidden tumors?