STAGE III PANCREATIC CANCER AJCC V8
Clinical trials for STAGE III PANCREATIC CANCER AJCC V8 explained in plain language.
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New combo therapy aims to keep advanced pancreatic cancer at bay
Disease control Recruiting nowThis study is testing whether a two-drug combination can help control advanced pancreatic cancer that has spread and cannot be surgically removed. The treatment is given as 'maintenance therapy' to patients whose cancer has stopped growing or shrunk after their initial chemothera…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Scientists combine three weapons in fight against tough pancreatic cancer
Disease control Recruiting nowThis early-stage study aims to find a safe dose for a new combination treatment for pancreatic cancer that has grown locally but cannot be removed by surgery. The treatment combines a targeted drug (olaparib), an immunotherapy drug (durvalumab), and radiation therapy. The main go…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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New drug combo aims to halt tough pancreatic cancer
Disease control Recruiting nowThis study is testing if adding an experimental pill called M3814 to a short, intense course of radiation therapy is safe and more effective than radiation alone for people with locally advanced pancreatic cancer. The goal is to better control the cancer and stop it from growing …
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for tough cancers: experimental drug enters first human testing
Disease control Recruiting nowThis is the first human study of a new chemotherapy drug called TR-002. It aims to find the safest dose and understand side effects for people with advanced solid tumors, including pancreatic cancer, that have stopped responding to standard treatments. The study will enroll 52 pa…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New hope for tough pancreatic cancers: can adding a targeted drug help patients live longer?
Disease control Recruiting nowThis study is for people with advanced pancreatic cancer that has stopped responding to their first treatment. It is testing if adding a targeted drug called panitumumab to standard second-line chemotherapy helps patients live longer than chemotherapy alone. The trial is specific…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New trial tests if switching PARP inhibitors can help control advanced cancers
Disease control Recruiting nowThis study is testing whether the drug talazoparib can help control advanced cancers in patients whose tumors have specific mutations in genes that help repair DNA damage. It is enrolling 36 adults with various advanced solid tumors (like breast, ovarian, prostate, pancreatic, an…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New drug duo targets Tough-to-Treat cancers
Disease control Recruiting nowThis study is testing the safety and effectiveness of a new two-drug combination for people with advanced solid tumors, including pancreatic cancer, that have spread or stopped responding to standard treatments. The trial aims to find the best dose and see if the drugs can help c…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Light therapy trial aims to boost immune attack on pancreatic cancer
Disease control Recruiting nowThis study is testing a new combination treatment for pancreatic cancer that cannot be removed by surgery or has spread. The approach uses a light-activated drug injected into the tumor to help the patient's own immune system, boosted by an immunotherapy drug (pembrolizumab), bet…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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Remote trial tests targeted pill for tough pancreatic cancer
Disease control Recruiting nowThis study is testing an oral drug called pemigatinib for adults with advanced pancreatic cancer that has specific genetic changes (FGFR alterations). The goal is to see if blocking these abnormal genes can stop tumor growth and improve quality of life. The trial is conducted ful…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Sameek Roychowdhury • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC
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New hope for tough pancreatic cancers: experimental drug combo enters human testing
Disease control Recruiting nowThis early-stage trial is testing whether adding a new oral drug called CA-4948 to standard chemotherapy is safe and tolerable for people with advanced pancreatic cancer that has spread or cannot be removed by surgery. The main goal is to find the highest dose that patients can h…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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High-Power radiation trial aims to extend lives in tough pancreatic cancer
Disease control Recruiting nowThis study is testing whether delivering a higher, more focused dose of radiation can help people with advanced pancreatic cancer live longer. It's for patients whose cancer hasn't spread widely and who have already had 4-6 months of chemotherapy. Participants are randomly assign…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Mar 23, 2026 15:14 UTC
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Can a simple ear tap fight cancer weight loss?
Symptom relief Recruiting nowThis study is testing if a simple, non-invasive therapy called ear acupressure can help improve appetite and prevent weight loss in people with certain advanced cancers. Researchers will recruit 66 patients with stomach, esophageal, or pancreatic cancer to see if applying small a…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Mar 12, 2026 13:52 UTC
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Scientists probe six drugs in race to outsmart pancreatic cancer
Knowledge-focused Recruiting nowThis early study aims to understand how six different investigational drugs affect the biology of pancreatic cancer tumors. It will enroll about 90 adults with various stages of pancreatic cancer. Participants take one of the drugs for about 10 days before a scheduled biopsy or s…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists probe new Drug's effect on deadly pancreatic tumors
Knowledge-focused Recruiting nowThis early research study aims to understand how an experimental drug called OMO-103 affects pancreatic cancer cells in patients. Twelve adults with advanced pancreatic cancer will receive two infusions of the drug and undergo tumor biopsies to see if it changes the tumor's biolo…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:39 UTC