STAGE III PANCREATIC CANCER AJCC V8
Clinical trials for STAGE III PANCREATIC CANCER AJCC V8 explained in plain language.
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Can a stronger radiation blast tame pancreatic cancer?
Disease control Recruiting nowThis phase III trial tests whether giving a higher dose of radiation can help people with locally advanced pancreatic cancer live longer. Participants must have already had 4-6 months of chemotherapy. The study compares higher-dose radiation to standard care (more chemo, observat…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New hope for Hard-to-Treat cancers: drug targets DNA repair weakness
Disease control Recruiting nowThis phase 2 trial is testing the drug talazoparib in people with advanced solid tumors that have specific mutations in DNA repair genes. Talazoparib works by blocking a protein called PARP, which cancer cells use to fix their damaged DNA, leading to cancer cell death. The study …
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New combo targets tough pancreatic tumors
Disease control Recruiting nowThis study tests a drug called M3814 combined with a special type of radiation for people with locally advanced pancreatic cancer (cancer that has spread nearby but not to distant organs). The goal is to find the safest dose and see if the combination helps stop tumor growth long…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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New hope for tough pancreatic cancer: targeted drug combo under study
Disease control Recruiting nowThis study tests whether adding a targeted drug called panitumumab to standard chemotherapy helps people with a specific type of advanced pancreatic cancer (KRAS wild-type) live longer. About 94 adults whose cancer has spread or can't be removed will be randomly assigned to get c…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New chemo cocktail shows promise for pancreatic cancer patients before surgery
Disease control Recruiting nowThis study tests whether giving a combination of three chemotherapy drugs (gemcitabine, cisplatin, and nab-paclitaxel) before surgery can help shrink pancreatic tumors and improve outcomes. It includes 36 adults with pancreatic cancer that is either removable or borderline remova…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New drug combo aims to shrink Hard-to-Treat tumors
Disease control Recruiting nowThis study tests two experimental drugs, ZEN003694 and entinostat, in people with advanced or treatment-resistant solid tumors, including pancreatic cancer. The goal is to find the safest dose and see if the combination can shrink tumors. About 49 participants will take part in t…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Arthritis drug shows promise against pancreatic cancer in early trial
Disease control Recruiting nowThis early-phase trial tests whether adding leflunomide, a drug used for rheumatoid arthritis, to standard chemotherapy (gemcitabine) is safe for people with advanced pancreatic cancer that cannot be removed by surgery. About 19 participants will receive the combination to find t…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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New drug TR-002 enters human testing for Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage trial is testing a new chemotherapy drug called TR-002 in about 52 people with advanced solid tumors, including pancreatic cancer that has stopped responding to standard treatments. The main goals are to find a safe dose and check for side effects. Researchers wi…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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New hope for pancreatic cancer: targeted pill studied in nationwide telemedicine trial
Disease control Recruiting nowThis study tests a drug called pemigatinib in people with advanced or metastatic pancreatic cancer that has certain changes in the FGFR gene. The drug aims to block these abnormal genes and stop tumor growth. About 40 adults will take the pill at home and be monitored through tel…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Sameek Roychowdhury • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Can a tailored web portal help pancreatic cancer patients exercise and eat better during chemotherapy?
Symptom relief Recruiting nowThis trial tests a web-based program called COMPASS that provides personalized exercise and nutrition advice, along with text messages, activity trackers, and coaching, for people with stage I-III pancreatic cancer receiving chemotherapy before surgery. The goal is to see if the …
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: NA • Sponsor: OHSU Knight Cancer Institute • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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New drug OMO-103 tested in early pancreatic cancer trial
Knowledge-focused Recruiting nowThis early phase 1 trial is studying how the drug OMO-103 affects pancreatic cancer cells in 12 patients with advanced or metastatic pancreatic ductal adenocarcinoma. The main goal is to see if the drug changes the tumor's biology by analyzing tissue samples before and after trea…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Pancreatic cancer drugs put to the test in early trial
Knowledge-focused Recruiting nowThis early phase trial is testing several targeted drugs in people with pancreatic cancer to see how they affect tumor biology. Researchers will compare tumor samples taken before and after treatment to understand which drugs might work best. The goal is not to treat the cancer d…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC