Pancreatic cancer drugs put to the test in early trial
NCT ID NCT04005690
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early phase trial is testing several targeted drugs in people with pancreatic cancer to see how they affect tumor biology. Researchers will compare tumor samples taken before and after treatment to understand which drugs might work best. The goal is not to treat the cancer directly, but to gather information that could guide future, more effective trials. About 90 participants with various stages of pancreatic cancer are being enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- cobimetinib, olaparib, onvansertib, azenosertib, saruparib, tremelimumab
- What this could lead to
- If successful, this study could help design better, more personalized treatments for pancreatic cancer by showing which drugs affect tumor biology.
- What could go wrong
- This is a very early, small study focused on measuring drug effects in tumors, not on curing or treating the disease. Many drugs tested in early trials do not lead to approved treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
OHSU Knight Cancer Institute
RECRUITINGPortland, Oregon, 97239, United States
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Other studies related to the condition(s) this trial covers.
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