STAGE II PANCREATIC CANCER AJCC V8

This study is testing whether a two-drug combination can help control advanced pancreatic cancer that has spread and cannot be surgically removed. The treatment is given as 'maintenance therapy' to patients whose cancer has stopped growing or shrunk after their initial chemothera…

This early-stage study aims to find a safe dose for a new combination treatment for pancreatic cancer that has grown locally but cannot be removed by surgery. The treatment combines a targeted drug (olaparib), an immunotherapy drug (durvalumab), and radiation therapy. The main go…

This study is testing whether the drug talazoparib can help control advanced cancers in patients whose tumors have specific mutations in genes that help repair DNA damage. It is enrolling 36 adults with various advanced solid tumors (like breast, ovarian, prostate, pancreatic, an…

This study is testing the safety and effectiveness of a new two-drug combination for people with advanced solid tumors, including pancreatic cancer, that have spread or stopped responding to standard treatments. The trial aims to find the best dose and see if the drugs can help c…

This study is testing a new combination treatment for pancreatic cancer that cannot be removed by surgery or has spread. The approach uses a light-activated drug injected into the tumor to help the patient's own immune system, boosted by an immunotherapy drug (pembrolizumab), bet…

This study is testing an oral drug called pemigatinib for adults with advanced pancreatic cancer that has specific genetic changes (FGFR alterations). The goal is to see if blocking these abnormal genes can stop tumor growth and improve quality of life. The trial is conducted ful…

This study is testing whether delivering a higher, more focused dose of radiation can help people with advanced pancreatic cancer live longer. It's for patients whose cancer hasn't spread widely and who have already had 4-6 months of chemotherapy. Participants are randomly assign…

This study is testing if a simple, non-invasive therapy called ear acupressure can help improve appetite and prevent weight loss in people with certain advanced cancers. Researchers will recruit 66 patients with stomach, esophageal, or pancreatic cancer to see if applying small a…

This early study aims to understand how six different investigational drugs affect the biology of pancreatic cancer tumors. It will enroll about 90 adults with various stages of pancreatic cancer. Participants take one of the drugs for about 10 days before a scheduled biopsy or s…

This early research study aims to understand how an experimental drug called OMO-103 affects pancreatic cancer cells in patients. Twelve adults with advanced pancreatic cancer will receive two infusions of the drug and undergo tumor biopsies to see if it changes the tumor's biolo…