STAGE III PANCREATIC CANCER AJCC V8
Clinical trials for STAGE III PANCREATIC CANCER AJCC V8 explained in plain language.
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New drug combo aims to shrink Hard-to-Treat tumors
Disease control Recruiting nowThis study tests two experimental drugs, ZEN003694 and entinostat, in people with advanced solid tumors that have stopped responding to standard treatments. The goal is to find the safest dose and see if the combination can shrink tumors. The trial includes up to 49 participants,…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 03:10 UTC
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New hope for pancreatic cancer: targeted drug combo enters phase 3 trial
Disease control Recruiting nowThis study tests whether adding the targeted drug panitumumab to standard chemotherapy helps people with a specific type of advanced pancreatic cancer (KRAS wild-type) live longer. About 94 adults whose cancer has spread or cannot be removed will receive either chemo alone or che…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated May 17, 2026 03:09 UTC
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New hope for pancreatic cancer: targeted pill study goes fully remote
Disease control Recruiting nowThis study tests a drug called pemigatinib in 40 adults with advanced or metastatic pancreatic cancer that has certain changes in the FGFR gene. The drug aims to block these abnormal genes and stop tumor growth. The study is done entirely through telemedicine, so participants can…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Sameek Roychowdhury • Aim: Disease control
Last updated May 15, 2026 11:58 UTC
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Experimental cocktail aims to shrink untreatable pancreatic tumors
Disease control Recruiting nowThis early-phase study tests whether adding bosentan to standard chemotherapy can help control pancreatic cancer that cannot be removed by surgery. About 21 adults will receive the combination to find the safest dose and check for side effects. The goal is to slow or stop tumor g…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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New combo targets tough pancreatic tumors
Disease control Recruiting nowThis study tests a drug called M3814 (Peposertib) combined with a special type of radiation for people with locally advanced pancreatic cancer that has spread to nearby tissues. The goal is to find the safest dose and see if the combination helps stop tumor growth longer than rad…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New cocktail of targeted drug, immunotherapy, and radiation takes on tough pancreatic cancer
Disease control Recruiting nowThis early-stage trial tests whether combining a targeted drug (olaparib), an immunotherapy (durvalumab), and radiation therapy is safe for people with locally advanced pancreatic cancer that cannot be surgically removed. About 18 participants will receive the combination after i…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Can higher radiation doses beat pancreatic cancer?
Disease control Recruiting nowThis study tests whether giving a higher dose of radiation can help people with locally advanced pancreatic cancer live longer. Participants must have already had 4-6 months of chemotherapy. The trial compares higher-dose radiation to standard care (more chemo, observation, or lo…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 14, 2026 12:04 UTC
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New drug TR-002 tested for tough-to-treat cancers
Disease control Recruiting nowThis early-stage study tests a new chemotherapy drug, TR-002, in about 52 people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find the safest dose and check for side effects. The study also looks at whether the drug can shr…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Could an arthritis drug help fight pancreatic cancer?
Disease control Recruiting nowThis early-phase trial tests whether adding leflunomide (an arthritis drug) to standard chemotherapy gemcitabine is safe and effective for people with advanced pancreatic cancer that cannot be removed by surgery. About 19 adults will receive the combination to find the best dose …
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE1 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 13, 2026 16:11 UTC
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New hope for advanced cancers with DNA repair flaws: PARP inhibitor trial opens
Disease control Recruiting nowThis study tests the drug talazoparib in adults with advanced solid tumors (like breast, prostate, ovarian, pancreatic, or stomach cancer) that have certain gene changes affecting DNA repair. The drug blocks a protein called PARP, which cancer cells need to fix their DNA, potenti…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:43 UTC
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Light-activated therapy may boost immune attack on hard-to-treat pancreatic cancer
Disease control Recruiting nowThis study tests a new combination for people with pancreatic cancer that cannot be surgically removed. It uses a light-activated drug (verteporfin) to make tumors more sensitive to immunotherapy (pembrolizumab) plus standard chemotherapy. The goal is to see if this approach shri…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New chemo cocktail aims to shrink pancreatic tumors before surgery
Disease control Recruiting nowThis study tests whether giving a combination of three chemotherapy drugs (gemcitabine, cisplatin, and nab-paclitaxel) before surgery can help shrink pancreatic tumors and improve outcomes. About 36 adults with pancreatic cancer that can be surgically removed will participate. Th…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated May 11, 2026 20:38 UTC
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Ear acupressure: a new hope for cancer appetite loss?
Symptom relief Recruiting nowThis study tests whether a simple, non-invasive technique called auricular acupressure (using small pellets on the ear) can help improve appetite and prevent weight loss in people with advanced stomach, esophageal, or pancreatic cancer. About 66 participants will receive either a…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated May 17, 2026 03:18 UTC
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New drug OMO-103 studied in pancreatic cancer patients to reveal tumor changes
Knowledge-focused Recruiting nowThis early phase 1 trial is studying how the drug OMO-103 affects pancreatic cancer cells in 12 patients with advanced or metastatic disease. The main goal is to see if the drug causes measurable changes in the tumor's biology by comparing tissue samples taken before and after tr…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated May 17, 2026 03:12 UTC
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New study peeks inside pancreatic tumors to find better drug targets
Knowledge-focused Recruiting nowThis study is for people with pancreatic cancer that can be removed by surgery or has spread. Researchers will give one of several drugs (cobimetinib, olaparib, onvansertib, azenosertib, AZD5305, or tremelimumab) for a short time before surgery or biopsy. By comparing tumor sampl…
Matched conditions: STAGE III PANCREATIC CANCER AJCC V8
Phase: EARLY_PHASE1 • Sponsor: OHSU Knight Cancer Institute • Aim: Knowledge-focused
Last updated May 17, 2026 03:09 UTC