SPINAL FUSION

This study tests whether giving iron supplements to teens with iron deficiency before scoliosis surgery can reduce the need for blood transfusions and improve thinking and physical recovery afterward. About 275 participants aged 10-26 will receive either iron pills or a placebo f…

This study tests whether a non-invasive device that gently stimulates a nerve in the ear can lower inflammation and pain after major spine surgery. About 50 adults having long-segment spinal fusion will be randomly assigned to receive the stimulation or standard care. Researchers…

This study tests whether giving intravenous iron to teens with iron deficiency before spinal fusion surgery can lower their need for blood transfusions. About 120 participants aged 10-19 will receive either IV iron or a placebo. The goal is to see if correcting iron levels improv…

This study tests whether the drug aprepitant can prevent nausea and vomiting in children and teens after scoliosis surgery. About 100 participants aged 8 to 18 will receive either aprepitant or standard care. The goal is to see if fewer kids need extra anti-nausea medicine after …

This early study looks at whether a nerve block called a thoracolumbar interfascial plane (TLIP) block can help older adults (65 and older) have less pain and a better recovery after spinal fusion surgery. The block uses a numbing medicine called bupivacaine. The study will enrol…

This study tests whether a back brace with red laser diodes can reduce chronic lower back pain in people who had spinal fusion or decompression surgery 1 to 5 years ago. Half of the 80 participants will wear the active laser brace, and half will wear a sham brace that looks the s…

This study compares two numbing medicines injected during scoliosis surgery to see which one better controls pain and reduces the need for strong opioid painkillers. About 128 teens aged 10 to 17 will be randomly assigned to receive either a long-acting numbing drug (liposomal bu…

This study looks at two different ways to place metal rods during long spinal fusion surgery to fix the back. Researchers will compare how often the rods break with each method by reviewing medical records of over 1200 patients aged 45 and older. The goal is to find out which tec…

This study looks at how major spine surgery damages the protective lining of blood vessels, called the glycocalyx. Researchers will measure a substance called Syndecan-1 in the blood of 30 people before and after surgery. The goal is to understand the extent of this damage and se…

This study compares two surgical approaches for single-level lumbar spinal stenosis: decompression alone versus decompression with spinal fusion. Researchers will track 86 patients aged 45-75 over two years to see if the simpler procedure works just as well. The goal is to determ…