SOLID TUMORS

This early-phase study tested a new medicine called BI 1821736 in 10 adults with advanced solid tumors that had not responded to other treatments. BI 1821736 is a special virus designed to kill cancer cells and help the immune system fight cancer. Participants received the drug b…

This study tested a new cancer pill, BI 907828, in adults with advanced cancers of the bile duct, pancreas, lung, or bladder that have a specific gene change (MDM2 amplified). Participants took the pill once every 3 weeks. The goal was to see if the drug could shrink tumors or sl…

This early-stage study tested a new drug, LY3127804, alone or with another drug (ramucirumab) in 62 people with advanced solid tumors. The goal was to check safety and find the right dose, but the study was stopped early. No serious side effects were seen, so the best dose could …

This study tested a combination of three drugs (azacitidine, pembrolizumab, and epacadostat) in people with advanced solid tumors, including certain lung and colorectal cancers. The goal was to see if the combination was safe and could shrink tumors. The trial was terminated earl…

This early-stage study tested a new drug called INCB062079 in 25 people with advanced liver cancer or other solid tumors that had spread. The main goal was to check the drug's safety and find the best dose. The study was stopped early, so results are limited.

This study tested a new drug, PF-08046031, in 11 adults with advanced melanoma or other solid tumors that had spread or had no standard treatment. The goal was to check safety and side effects, and to find the right dose. The trial was terminated early, so results are limited.

This study tested an experimental drug called INCB057643 in 137 people with advanced cancers that had stopped responding to standard treatments. The goal was to find a safe dose and check for side effects, both when given alone and with other cancer drugs. The trial was terminate…

This early-phase study aimed to test the safety and dosing of an experimental drug called INCB086550 in Japanese adults with advanced solid tumors that had stopped responding to standard treatments. Only 3 participants were enrolled before the study was terminated early. The main…

This early-stage study tested an experimental drug called ABBV-303, alone or with another drug (budigalimab), in 27 adults with advanced solid tumors that had stopped responding to standard treatments. The main goal was to check safety and find the right dose. The study was stopp…

This early-phase study tested a new drug called eciskafusp alfa, alone or with another immunotherapy (atezolizumab), in 189 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety and find the right dose. The study…

This study looked at how the body absorbs, breaks down, and gets rid of a drug called subasumstat in people with advanced solid tumors that had no other treatment options. Only 3 adults took part before the study was stopped early. The goal was to measure the drug's path through …