New cancer drug trial halted early – what we know

NCT ID NCT02711137

Terminated Disease control Sponsor: Incyte Corporation Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called INCB057643 in 137 people with advanced cancers that had stopped responding to standard treatments. The goal was to find a safe dose and check for side effects, both when given alone and with other cancer drugs. The trial was terminated early, so results are limited.

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Conditions

The condition(s) this trial relates to.

breast neoplasm colorectal neoplasm diffuse large B-cell lymphoma glioblastoma hematopoietic and lymphoid cell neoplasm leukemia lymphoma Myelodysplastic Syndromes Myeloproliferative Disorders neoplasm non-Hodgkin lymphoma non-small cell lung carcinoma ovarian cancer pancreatic neoplasm plasma cell myeloma primary myelofibrosis prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMORS

Contacts and locations

Locations

Hematology - Oncology Associates of Treasure Coast

Port Saint Lucie, Florida, 34952, United States
Huntsman Cancer Institute

Salt Lake City, Utah, 84112, United States
HÔPITAL SAINT-LOUIS, Service Hématologie Adultes

Paris, 75010, France
Institut Jules Bordet, Clinical Trial Conduct Unit

Brussels, B-1000, Belgium
MultiCare Institute for Research and Innovation

Tacoma, Washington, 98405, United States
Oncology Consultants, P.A.

Houston, Texas, 77030, United States
Sarah Cannon Research Institute at Health One

Denver, Colorado, 80218, United States
Sylvester Comprehensive Cancer Center

Miami, Florida, 33136, United States
The Methodist Hospital

Houston, Texas, 77030, United States
University of Alabama

Birmingham, Alabama, 35294-3300, United States
University of California

La Jolla, California, 92093, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States
University of Minnesota

Minneapolis, Minnesota, 55455, United States
University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, 27599, United States
University of Rochester, Wilmot Cancer Center

Rochester, New York, 14642, United States
Wake Forest Baptist Health

Winston-Salem, North Carolina, 27157, United States
Washington University

St Louis, Missouri, 63110, United States
Yale University

New Haven, Connecticut, 06510, United States

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