SHORT BOWEL SYNDROME
Clinical trials for SHORT BOWEL SYNDROME explained in plain language.
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New drug could help people with short bowel syndrome ditch IV nutrition
Disease control Recruiting nowThis phase 2 trial tests a new drug called HM15912 (sonefpeglutide) in 18 adults with short bowel syndrome who need intravenous nutrition. The study aims to see if the drug is safe and can help the gut absorb more nutrients, potentially reducing the need for IV support. Participa…
Matched conditions: SHORT BOWEL SYNDROME
Phase: PHASE2 • Sponsor: Hanmi Pharmaceutical Company Limited • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New device aims to grow gut length for short bowel patients
Disease control Recruiting nowThis study tests a device called the Eclipse XL1 that is placed inside the body to slowly stretch and lengthen the remaining small intestine in people with short bowel syndrome. The goal is to improve nutrition and reduce the need for intravenous feeding. The study will enroll 40…
Matched conditions: SHORT BOWEL SYNDROME
Phase: NA • Sponsor: Eclipse Regenesis, Inc. • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Could a weekly shot free short bowel patients from IV bags?
Disease control Recruiting nowThis phase 3 trial tests glepaglutide, a synthetic hormone given as a twice-weekly injection, in 90 adults with short bowel syndrome who rely on IV nutrition. The goal is to see if the drug can safely reduce the amount of IV support needed. Participants will be randomly assigned …
Matched conditions: SHORT BOWEL SYNDROME
Phase: PHASE3 • Sponsor: Zealand Pharma • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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New device could free kids with short bowel from IV nutrition
Disease control Recruiting nowThis study tests a device called RELiZORB that pre-digests fat in tube feedings for children with short bowel syndrome who rely on IV nutrition. The goal is to see if it helps them absorb more nutrients and reduce their need for IV feeding. About 32 children aged 2 to 18 will use…
Matched conditions: SHORT BOWEL SYNDROME
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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Weekly shot could help people with short bowel syndrome absorb more fluids
Disease control Recruiting nowThis phase IIa trial tests whether FT1, a lab-made version of a natural gut hormone, is safe and helps reduce fluid loss in adults with short bowel syndrome. Participants receive weekly injections of FT1 or a placebo for five weeks. The study measures changes in stool weight and …
Matched conditions: SHORT BOWEL SYNDROME
Phase: PHASE2 • Sponsor: Chongqing Peg-Bio Biopharm Co., Ltd. • Aim: Disease control
Last updated Jul 17, 2026 00:00 UTC
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New drug could cut IV nutrition needs for short bowel patients
Disease control Recruiting nowThis phase 3 trial tests a drug called teduglutide in 13 Chinese adults with short bowel syndrome who rely on IV nutrition. Participants get a daily injection for 24 weeks to see if it reduces their need for IV support. The study also checks safety and how the body processes the …
Matched conditions: SHORT BOWEL SYNDROME
Phase: PHASE3 • Sponsor: Takeda • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Could a Plant-Based powder cut the need for IV nutrition?
Disease control Recruiting nowThis phase 2 trial tests crofelemer, a plant-based oral powder, in 18 adults with short bowel syndrome and intestinal failure who rely on IV nutrition. Participants receive either a low dose, a higher dose, or a placebo for 24 weeks. The goal is to see if crofelemer safely reduce…
Matched conditions: SHORT BOWEL SYNDROME
Phase: PHASE2 • Sponsor: Napo Therapeutics, S.p.A. • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New shot could cut IV feeding for short bowel patients
Disease control Recruiting nowThis study tests a drug called PJ009 in people aged 14 and older with short bowel syndrome who rely on IV nutrition. The goal is to see if daily shots can safely reduce the amount of IV nutrition needed. Participants will receive either PJ009 or a placebo for 24 weeks, then all w…
Matched conditions: SHORT BOWEL SYNDROME
Phase: PHASE3 • Sponsor: Chongqing Peg-Bio Biopharm Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Could a Plant-Based drug cut IV nutrition needs for short bowel patients?
Symptom relief Recruiting nowThis early-phase pilot study is testing a drug called crofelemer in 6 adults with short bowel syndrome who have an ileostomy and need IV nutrition. The goal is to see if crofelemer can reduce ostomy output and the amount of IV support needed over 12 weeks. Participants take the d…
Matched conditions: SHORT BOWEL SYNDROME
Phase: EARLY_PHASE1 • Sponsor: Lindsey Russell, MD • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Measuring hidden energy needs: a clue to better nutrition for gut failure patients
Knowledge-focused Recruiting nowThis study measures how many calories people burn at rest, comparing healthy adults to those with intestinal failure (a condition where the gut cannot absorb enough nutrients). Researchers will also look at body composition and inflammation markers. The goal is to find out if ene…
Matched conditions: SHORT BOWEL SYNDROME
Phase: NA • Sponsor: Institute of Oncology Ljubljana • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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New 'Disk' tool aims to speed up Quality-of-Life checks for short bowel patients
Knowledge-focused Recruiting nowThis study is creating a faster quality-of-life tool for people with short bowel syndrome, who often need long-term nutrition support. Researchers will compare a new simple 'disk' questionnaire to a longer existing one in 100 adults. The goal is to make regular check-ins easier f…
Matched conditions: SHORT BOWEL SYNDROME
Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC