Could a Plant-Based powder cut the need for IV nutrition?
NCT ID NCT06904872
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests crofelemer, a plant-based oral powder, in 18 adults with short bowel syndrome and intestinal failure who rely on IV nutrition. Participants receive either a low dose, a higher dose, or a placebo for 24 weeks. The goal is to see if crofelemer safely reduces the amount of IV nutrition and stool volume needed.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Crofelemer (oral powder)
- What this could lead to
- If it works, crofelemer could help reduce the amount of IV nutrition needed for people with short bowel syndrome, improving daily life.
- What could go wrong
- This is a small, early-phase trial with only 18 participants, so results may not apply to everyone. The drug may not work better than placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Asklepios Klinik St. Georg
RECRUITINGHamburg, 20099, Germany
-
Azienda Ospedaliera Universitaria Federico II
RECRUITINGNaples, 80131, Italy
-
Azienda Ospedaliero-Universitaria di Bologna Policlinico S. Orsola-Malpighi
RECRUITINGBologna, 40138, Italy
-
Charité Universitätsmedizin
RECRUITINGBerlin, 10117, Germany
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Ospedale Università di Padova
RECRUITINGPadova, 35128, Italy
-
Universitäatsklinik RWTH
RECRUITINGAachen, 52074, Germany
-
Universitätsklinikum
RECRUITINGEssen, 45147, Germany
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Universitätsmedizin
RECRUITINGRostock, 18057, Germany
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