SENSORINEURAL HEARING LOSS

This phase 2 trial tests whether the drug SPI-1005 can prevent hearing loss and reduce side effects like tinnitus and vertigo in adults receiving a cochlear implant. Forty participants will take either the drug or a placebo for 6 months, starting 2 days before surgery. The study …

This study tests an experimental device called the Tinnitus Implant System for adults with moderate to severe chronic tinnitus. The implant is placed behind the ear and sends electrical signals to the hearing nerve. Researchers will measure how much tinnitus loudness changes over…

This study tests whether Yiyuancong, a traditional Chinese medicine made from food-like ingredients, can help people with sudden hearing loss. About 128 adults aged 18-60 will take the formula for 1-2 months, and their hearing will be measured with standard tests. The goal is to …

This study aims to create a step-by-step guide for adapting a children's speech hearing test, called MATCH, into different languages. Researchers will test the adapted test on 120 children, including those with normal hearing and those with hearing loss, to make sure it works cor…

This study tests whether acetylcysteine, a drug often used for other purposes, can prevent hearing loss caused by cisplatin chemotherapy. About 40 adults receiving high-dose cisplatin will get either acetylcysteine or a placebo after each chemo session. Researchers will measure h…

This study tests a new Bluetooth Low Energy Audio feature in Nucleus 8 and Kanso 3 sound processors for cochlear implants. Twenty experienced adult users will try wireless microphones at home and in the lab to see if they can hear speech better in noisy places like classrooms. Th…

This study is testing whether changing the low-frequency settings on a cochlear implant can improve hearing for people who are deaf in one ear but have normal hearing in the other. Twenty-two adults will try four different sound maps during their first month after implant activat…

This pilot study tests whether a new training program called SEBAR can improve confidence and success with over-the-counter (OTC) hearing aids. Twenty-seven adults with mild-to-moderate hearing loss who have never used hearing aids will wear OTC devices for a week and answer ques…

This study tests three hearing aid adjustments to help people with hearing loss understand speech in noisy, multi-talker settings. Researchers will compare how well 220 participants (with normal hearing or hearing loss) can pick out words and sense where sounds come from, with an…

This study analyzes dried blood spots from 630 newborns to find protein and RNA markers that could predict which babies with congenital CMV will develop hearing loss or other problems. Researchers will compare samples from infected babies who had complications, those who did not,…

This study aims to understand why people with Turner syndrome often lose their hearing. Researchers will look at genetic and epigenetic markers in 150 adults aged 18-60. Participants will have hearing, balance, blood, and imaging tests. The goal is to find new ways to treat or de…

This study collects information from 450 newborns who fail their initial hearing screening. Doctors will test them for congenital CMV, a common infection that can cause hearing loss and other problems. The goal is to see how often CMV is found and to improve follow-up care for af…

This study explores whether a brain-scanning technique called fNIRS can measure how well hearing aids help young children with hearing loss. Researchers will compare brain activity in 40 infants (3-18 months old) with normal hearing and those using hearing aids. If fNIRS proves r…

This study follows 19 adults with hearing loss who already received a cochlear implant that releases a steroid to reduce inflammation. Researchers will check how well the implant works over 5 years by measuring electrical signals and tracking any side effects. The goal is to see …

This study explores whether a test that measures brain waves in response to visual images can be used in a new way for people with hearing loss. Researchers will compare these brain responses to standard hearing tests and thinking skills tests. The goal is to see if this test can…

This study looks at how children and adults with cochlear implants and some natural hearing understand speech in noisy environments and locate where sounds come from. Researchers will test 160 participants, including those with normal hearing and those with cochlear implants. The…