SAFETY

This study is checking how safe the Prevenar 20 vaccine is once it's used in Korea. About 660 people aged 6 weeks and older who are prescribed the vaccine will get one dose. Researchers will track any side effects for 28 days after vaccination.

This early-stage study tests a new drug called GenSci098 in people with active thyroid eye disease (TED). The main goal is to see if the drug is safe and tolerable when given as one or multiple injections under the skin. About 76 adults aged 18 to 75 with active TED will take par…

This study tests a new drug, HY07121, in 258 adults with advanced solid tumors that have not responded to standard treatments. The goal is to check if the drug is safe and can shrink tumors. Participants receive the drug by infusion, and researchers monitor side effects and tumor…

This study tests a new drug combination for people with a common type of advanced colorectal cancer that has not responded to initial treatment. The trial will enroll 40 adults and measure how many patients see their tumors shrink by at least 30% for over a month. The approach co…

This study tests an experimental drug, HYP-2090PTSA, in people with advanced solid tumors that have a specific genetic change called KRAS mutation. The trial has two parts: first, finding the safest dose, and then testing how well that dose works in certain cancers. About 257 adu…

This early-stage study tests whether a new stem cell product (XS228) is safe for people with recent spinal cord injuries. The cells are made from special stem cells and are injected into the spine to possibly help repair nerve damage. The study includes 12 adults with injuries be…

This early-stage study tests a single injection of a new drug called GenSci098 in 24 adults with Graves' disease, a condition where the thyroid is overactive. The main goal is to check if the drug is safe and how the body handles it. Participants will be monitored for side effect…

This early-stage study tests a new injection called GenSci134 in healthy adults and in patients with adult growth hormone deficiency. The main goal is to check safety and side effects. The study is currently recruiting 64 participants.

This early-stage study tests whether stem cells from the amniotic sac can help heal painful wounds in people with calciphylaxis, a rare and serious condition linked to chronic kidney disease. Nine adults aged 18-75 will receive the treatment and be monitored for wound healing and…

This study tests an experimental drug called IRL757 in 75 people with Parkinson's disease who also have apathy (loss of interest or motivation). The main goal is to see if the drug is safe and tolerable over 12 weeks. Researchers will also check if it helps improve apathy symptom…

This study compares a newer pain medicine (oliceridine) with two standard ones (morphine and sufentanil) for controlling pain after lower back surgery. About 90 adults having lumbar spine surgery will receive one of the three drugs through a patient-controlled pump. Researchers w…

This early-stage study tests whether psilocybin (the active ingredient in magic mushrooms) combined with talk therapy can safely reduce demoralization—a deep sense of hopelessness—in people with advanced cancer. Fifteen adults aged 18-70 with stage 3 or 4 cancer and high demorali…

This study is checking the long-term safety of a supplement called palmitoylethanolamide (PEA) in 200 healthy adults aged 18 and older. Participants will take either PEA or a placebo daily for 12 months and have regular check-ups, blood tests, and safety assessments. The goal is …

This early-stage study tests whether a single inhaled dose of RCS-21 is safe and tolerable in 24 healthy volunteers aged 18 to 64. Participants receive either the drug or a placebo and are closely monitored for side effects and how the drug moves through the body. The study does …

This early-stage study tests a new antibiotic combination (ceftibuten-ledaborbactam) in about 46 healthy adults aged 18-55. The goal is to check safety and how the drug moves through the body, not to treat any disease. Results will help decide if further testing is possible.

This study surveys 400 doctors, nurses, and respiratory therapists worldwide to understand how non-invasive ventilation (breathing support via mask or helmet) is used outside intensive care units. The goal is to identify which patients receive it, how well it works, and what chal…

This early study tests whether taking curcumin (a compound in turmeric) for two weeks can cross into the brain and attach to amyloid-beta proteins, which are linked to Alzheimer's disease. Researchers will use special eye imaging to see if these proteins become visible, and also …