SAFETY

This study tested if injecting the antifungal drug fluconazole directly into the cornea is safe and effective for treating fungal keratitis, a serious eye infection. 40 patients with lab-confirmed fungal infections that were sensitive to fluconazole took part. The researchers mea…

This early-phase study tested whether a treatment made from a patient's own immune cells (tumor-infiltrating lymphocytes) is safe for people with advanced solid tumors like melanoma, cervical cancer, and lung cancer. 43 participants received the therapy to find the best dose and …

This study tested a treatment called GC101 TIL for people with advanced melanoma that had stopped responding to standard therapies. Doctors took immune cells from each patient's own tumor, multiplied them in a lab, and gave them back to the patient. The goal was to see if this ap…

This study tested a new supplement called KGA-10 (a heat-killed bacterium) in 107 healthy adults. Participants took either the supplement or a placebo daily for 8 weeks. Researchers measured stress, sleep quality, general well-being, and inflammation through surveys and blood sam…

This study looked at whether taking a dietary supplement for 60 days could improve thinking skills and mood in 75 university students. Participants were split into three groups: two received different supplements, and one got a placebo. Researchers measured changes in self-confid…

This study tested a numbing injection given around both eyes to see if it safely controls pain during cataract surgery. Fifty adults received the injection, and researchers measured their pain and satisfaction. The goal was to find a better way to keep patients comfortable during…

This study tested a community bike safety program for 195 kids ages 9 to 12. Some kids took a 12-hour safety class, some took the class plus a parent training session, and others received no training. All bikes were equipped with GPS and video cameras to track real-world riding b…

This study checked whether a specific oral probiotic (Streptococcus salivarius eK12) is safe for healthy adults to take. A total of 29 participants in Pakistan and Italy received the probiotic or a placebo. Researchers monitored for side effects and changes in vital signs, blood …

This study tested an online decision aid for 500 informal caregivers of people with dementia who have access to firearms. The goal was to see if the tool helps caregivers feel more prepared and confident in making safety decisions. The study did not provide any treatment for deme…

This study looked at whether it's safe for pregnant women to get the COVID-19 and flu vaccines at the same time or if they should wait 1-2 weeks between shots. About 100 pregnant women took part, and researchers tracked side effects and birth outcomes like preterm birth. The goal…

This study tested if giving the drug pasireotide with a reusable pen works as well as using a traditional syringe. Forty healthy adults received single doses by both methods to compare drug levels and safety. The goal was to see if the pen is a reliable alternative for future pat…

This study looked at how safe kratom is and how the body processes it in healthy adults who have used opioids recreationally. 40 participants received single rising doses of kratom to monitor side effects and drug levels. The goal was to gather basic safety information, not to tr…

This study looked at how well a new type of glutathione supplement (called LipoMicel) is absorbed by the body compared to standard versions. Sixteen healthy adults took the supplement daily for 30 days, and researchers measured levels in the blood and checked for safety. The goal…

This early-stage study tested whether a purified exosome product (PEP) is safe when injected into the skin of healthy adults. Eight participants received the injection and were monitored for side effects. The goal was to check for any immediate reactions or lab changes, not to tr…

This study tested a new way to teach personal safety to 60 children aged 4-5. Half of the kids took part in a special program using games and activities based on multiple intelligences theory, while the other half had regular lessons. The program aimed to improve children's knowl…

This early-stage study tested the safety and how the body handles a new drug called Y-3 in 20 healthy adults. Participants received a single dose of either 40 mg, 60 mg, or a placebo. The goal was to measure drug levels in the blood and check for any side effects, not to treat a …