RENAL CELL CARCINOMA (RCC)

This study is testing a new way to take the kidney cancer drug cabozantinib. Researchers want to see if taking a higher dose for one or two days, then skipping a day, works as well as taking a smaller dose every single day. They are checking if this new schedule keeps enough medi…

This study is testing if a special type of scan (PET/CT) can safely tell doctors when to pause treatment for people with advanced kidney cancer. It is for patients who have responded well to at least a year of standard drug therapy. The goal is to see if a closely monitored break…

This study compares two surgical approaches for removing diseased or cancerous kidneys: laparoscopic (using small incisions and a camera) versus traditional open surgery. Researchers will measure which method leads to shorter hospital stays, fewer complications, better recovery, …

This early-stage study is testing a new type of personalized immune cell therapy (CAR-T) for people with advanced solid tumors that have a specific marker called CD70. The main goals are to find a safe dose and see how the body handles the treatment. It is for adults with cancers…

This early-stage study is testing a new drug called Sapu003 in people with advanced cancers that have spread or cannot be removed by surgery. The main goal is to find the safest and most effective dose, and to see how the body processes the drug. The study includes 27 adults with…

This early-stage study is testing a new drug called GI-108 in people with advanced or spreading solid tumors, including lung, head and neck, pancreatic, and kidney cancers. The main goals are to find a safe dose and see if the drug shows any signs of helping to shrink tumors. The…

This study is testing a three-part treatment given before surgery for advanced kidney cancer. The goal is to shrink the tumor and make it easier to remove completely. The treatment involves a procedure to block the tumor's blood supply, followed by immunotherapy and targeted drug…

This study is testing whether blocking a kidney tumor's blood supply before freezing it makes the treatment safer and more effective. Researchers are enrolling 25 adults with medium-sized kidney cancer (4-7cm) that hasn't spread. The goal is to see if this two-step procedure help…

This study is testing a new drug called XL092, both by itself and in combination with other immunotherapy drugs, for people with advanced solid tumors that cannot be removed by surgery. The main goals are to find safe doses and see if the treatments can shrink tumors or slow thei…

This large, late-stage trial is testing if a two-drug combination works better than the current standard single drug to prevent kidney cancer from returning after surgery. It will enroll over 1,000 patients whose cancer is at high risk of coming back. The goal is to see if adding…

This is the first study in people to test a new drug called LB-LR1109. The main goal is to find a safe and tolerable dose for patients with advanced or metastatic solid tumors, including lung, head and neck, kidney, bladder cancers, and melanoma. The study will test the drug alon…

This research study aims to understand how the immune system responds to kidney cancer by examining tissue samples from patients. Researchers will collect small amounts of tumor and lymph node tissue during standard medical procedures to study immune cells. The goal is to learn h…