New combo therapy aims to shrink kidney tumors before surgery

NCT ID NCT07172386

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This phase 2 trial tests a three-part approach for advanced kidney cancer: first, a procedure to block blood flow to the tumor, then two drugs (toripalimab and axitinib) before surgery, followed by more toripalimab after surgery. The goal is to see if this makes surgery more successful and controls the cancer longer. The study involves 40 participants and is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

toripalimab and axitinib

What this could lead to

If successful, this combination could improve surgical outcomes and control advanced kidney cancer more effectively, potentially extending survival.

What could go wrong

This is a small, early-phase trial with only 40 participants. The treatment may cause side effects, and results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Tianjin Medical University Second Hospital

    RECRUITING

    Tianjin, Tianjin Municipality, 300211, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••