Could a PET scan let kidney cancer patients pause treatment?

NCT ID NCT07175480

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This phase 2 trial is testing whether PET/CT scans can safely guide treatment pauses in people with advanced kidney cancer. Participants who have responded well to at least 12 months of standard therapy (immunotherapy plus targeted drugs) will stop treatment and be monitored with PET scans. The goal is to see if this approach can maintain cancer control while giving patients a break from medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

PD-1/PD-L1 immune checkpoint inhibitor and VEGFR-tyrosine kinase inhibitor (treatment pause strategy)

What this could lead to

If successful, this could offer a way for some patients with advanced kidney cancer to safely take breaks from treatment, reducing side effects and improving quality of life.

What could go wrong

This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The treatment pause could lead to cancer progression in some patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China

    RECRUITING

    Nanjing, Jiangsu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••