PULPITIS - IRREVERSIBLE
Clinical trials for PULPITIS - IRREVERSIBLE explained in plain language.
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New Tooth-Saving materials put to the test against standard treatment
Disease control CompletedThis study tested three different materials used to treat severe, irreversible tooth inflammation. 72 adults with painful molars received a procedure where the damaged pulp was removed and covered with one of the materials. The goal was to see if newer materials (TheraCal LC and …
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Cukurova University • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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New, less invasive tooth treatments for kids show promise
Disease control CompletedThis study tested two simpler procedures called Lesion Sterilization and Tissue Repair (LSTR) against the standard root canal treatment (pulpectomy) for infected baby molars in 66 children. One LSTR method cleaned the root canals, while the other only removed the top pulp and pla…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Cairo University • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New Tooth-Saving technique could replace root canals
Disease control CompletedThis study tested a less invasive treatment called vital pulp therapy against standard root canals for teeth with severe pulp inflammation. In the new approach, dentists removed only the inflamed pulp and placed a natural blood-derived material (PRF) to help the tooth heal. Forty…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Universidad Central de Venezuela • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Dentists put cold, heat, and electric tooth tests to the test
Diagnosis CompletedThis study tested how well cold, heat, and electric pulp tests detect tooth nerve health in 175 adults needing root canals. Researchers compared test results to direct observation of nerve bleeding during treatment. The goal was to find which test is most accurate for diagnosing …
Matched conditions: PULPITIS - IRREVERSIBLE
Sponsor: Istanbul University • Aim: Diagnosis
Last updated Jun 27, 2026 09:09 UTC
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New study tests which root canal cleaning method hurts less
Symptom relief CompletedThis study looked at four different ways to activate the cleaning solution used during root canals: laser, sonic, ultrasonic, and simple needle irrigation. The goal was to see which method causes the least pain after the procedure and how much debris gets pushed out of the tooth.…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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Pre-Root canal painkiller cuts Post-Procedure pain, study finds
Symptom relief CompletedThis study looked at whether taking a single dose of the painkiller diclofenac before a root canal can reduce pain afterward. 160 adults with tooth pain from irreversible pulpitis were split into two groups: one took 100 mg of diclofenac 30 minutes before the procedure, and the o…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: College of Physicians and Surgeons Pakistan • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Could probiotics ease tooth pain after root canal?
Symptom relief CompletedThis study tested whether probiotics, a double antibiotic paste, or calcium hydroxide paste can reduce pain after root canal treatment in adults with severe tooth inflammation (irreversible pulpitis). 75 participants received one of the three pastes placed inside the tooth and re…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Dow University of Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 08:02 UTC
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Can a steroid or cold water ease tooth pain after root treatment?
Symptom relief CompletedThis study looked at 72 adults with a painful tooth condition called irreversible pulpitis. During a dental procedure to remove the infected pulp, researchers tested whether rinsing the tooth with a dexamethasone solution or cold saline could reduce pain afterward. The goal was t…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Cukurova University • Aim: Symptom relief
Last updated Jun 27, 2026 07:59 UTC
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Alcohol may weaken dental anesthesia, new study suggests
Knowledge-focused CompletedThis study looked at whether alcohol consumption affects the success of local anesthesia for people with a painful tooth condition called irreversible pulpitis. Researchers gave 70 patients (35 who drink alcohol and 35 who don't) a standard numbing injection and measured pain dur…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Jamia Millia Islamia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:39 UTC
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Root canal pain relief may depend on your DNA
Knowledge-focused CompletedThis study looked at whether a specific gene variation (SCN9A rs6746030) affects the success of numbing injections for root canal treatment. Researchers compared 200 patients with irreversible pulpitis who either had successful or failed anesthesia. By analyzing DNA from cheek sw…
Matched conditions: PULPITIS - IRREVERSIBLE
Phase: NA • Sponsor: Jamia Millia Islamia • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC