Could probiotics ease tooth pain after root canal?
NCT ID NCT07270159
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether probiotics, a double antibiotic paste, or calcium hydroxide paste can reduce pain after root canal treatment in adults with severe tooth inflammation (irreversible pulpitis). 75 participants received one of the three pastes placed inside the tooth and reported their pain levels over a week. The goal was to find which works best for pain relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Probiotics, double antibiotic paste, and calcium hydroxide paste
- What this could lead to
- If probiotics work, this could point toward a more natural way to manage pain after root canal treatment.
- What could go wrong
- This is a small, completed trial with only 75 participants, so results may not apply to everyone. Probiotics may not reduce pain better than standard treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dow International Dental College
Karachi, Sindh, 12345, Pakistan
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