Could probiotics ease tooth pain after root canal?
NCT ID NCT07270159
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether probiotics, a double antibiotic paste, or calcium hydroxide paste can reduce pain after root canal treatment in adults with severe tooth inflammation (irreversible pulpitis). 75 participants received one of the three pastes placed inside the tooth and reported their pain levels over a week. The goal was to find which works best for pain relief.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Probiotics, double antibiotic paste, and calcium hydroxide paste
What this could lead to
If probiotics work, this could point toward a more natural way to manage pain after root canal treatment.
What could go wrong
This is a small, completed trial with only 75 participants, so results may not apply to everyone. Probiotics may not reduce pain better than standard treatments.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Dow International Dental College
Karachi, Sindh, 12345, Pakistan