Pre-Root canal painkiller cuts Post-Procedure pain, study finds

NCT ID NCT07271654

Completed Symptom relief Sponsor: College of Physicians and Surgeons Pakistan Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at whether taking a single dose of the painkiller diclofenac before a root canal can reduce pain afterward. 160 adults with tooth pain from irreversible pulpitis were split into two groups: one took 100 mg of diclofenac 30 minutes before the procedure, and the other did not. The results showed that those who took the medicine were much more likely to be pain-free at 6 and 12 hours after the root canal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Diclofenac Sodium
What this could lead to: If confirmed, taking a single dose of diclofenac before a root canal could help many people have a more comfortable recovery.
What could go wrong: This is a small, completed trial. Results may not apply to all patients or settings, and diclofenac can cause side effects like stomach upset or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PULPITIS - IRREVERSIBLE

Contacts and locations

Locations

Saidu College of dentistry,Swat

Swat, Pakistan

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