Pre-Root canal painkiller cuts Post-Procedure pain, study finds
NCT ID NCT07271654
First seen Jun 24, 2026 · Last updated Jun 24, 2026
Summary
This study looked at whether taking a single dose of the painkiller diclofenac before a root canal can reduce pain afterward. 160 adults with tooth pain from irreversible pulpitis were split into two groups: one took 100 mg of diclofenac 30 minutes before the procedure, and the other did not. The results showed that those who took the medicine were much more likely to be pain-free at 6 and 12 hours after the root canal.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Saidu College of dentistry,Swat
Swat, Pakistan
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Diclofenac Sodium
What this could lead to
If confirmed, taking a single dose of diclofenac before a root canal could help many people have a more comfortable recovery.
What could go wrong
This is a small, completed trial. Results may not apply to all patients or settings, and diclofenac can cause side effects like stomach upset or allergic reactions.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.