PROSTATIC NEOPLASMS

This study is testing whether different pill versions of two prostate cancer drugs (niraparib and abiraterone acetate) work similarly in the body. It involves 136 men with advanced prostate cancer that has spread and stopped responding to standard hormone therapy. The main goal i…

This study is testing whether a diet rich in fish oils (omega-3s) combined with a medication called dutasteride can slow down or control the progression of low-risk prostate cancer. It involves 120 men who are already on 'active surveillance' for their cancer. Participants follow…

This study provided early access to the drug apalutamide for men with a specific type of advanced prostate cancer that had stopped responding to standard hormone therapy but had not yet spread to other parts of the body. The main goal was to collect safety information while the d…

This early-stage study is testing a new radioactive antibody drug called JNJ-69086420 for men with advanced prostate cancer that has spread and stopped responding to standard hormone treatments. The main goal is to find the safest and most effective dose by monitoring side effect…

This early-stage study is testing the safety and how the body processes a prostate cancer drug called apalutamide in Chinese men. It involves 19 participants whose prostate cancer has spread and stopped responding to standard hormone treatments. The main goals are to check drug l…

This large, late-stage trial is testing if adding a new targeted radiation drug (177Lu-PSMA-617) to standard hormone therapy works better than standard therapy alone for men whose prostate cancer has recently spread. The drug is designed to seek out and deliver radiation directly…

This large study is testing whether adding a new drug called apalutamide to standard radiation and hormone therapy helps men with high-risk prostate cancer. It aims to see if this combination keeps the cancer from spreading to other parts of the body for a longer time. The trial …

This large Phase 3 trial tested whether the drug apalutamide (ARN-509) could delay the spread of prostate cancer in men whose cancer had stopped responding to standard hormone therapy but hadn't yet spread to other body parts. About 1,200 men were randomly assigned to receive eit…

This study tested whether a new targeted radiation drug (177Lu-PSMA-617) works better than switching to a different standard hormone therapy for men with advanced prostate cancer that has spread and stopped responding to prior hormone treatments. The drug seeks out and delivers r…

This large, late-stage study is testing if adding the drug apalutamide to standard radiation and hormone therapy is better at delaying the spread of prostate cancer in high-risk patients who have already had surgery. It will involve about 693 men and use advanced PET scans to clo…

This is an early-stage study to find a safe dose of a new experimental treatment called JNJ-75229414 for men with advanced prostate cancer that has spread and no longer responds to standard hormone therapy. The treatment involves collecting a patient's own immune cells (T cells),…

This study is testing whether a 16-week home exercise program can slow the progression of prostate cancer in Black men who are on active surveillance (monitoring without immediate treatment). Researchers want to see if high-intensity interval training (HIIT) can help control canc…

This study is testing whether the drug apalutamide can delay the rise of a prostate cancer marker (PSA) in Chinese men whose cancer has stopped responding to standard hormone therapy but hasn't spread. It will compare apalutamide against a placebo in 75 participants. The main goa…

This large, late-stage study tested whether adding a new drug called apalutamide to a standard two-drug therapy could better control advanced prostate cancer that has spread and stopped responding to hormone therapy. It involved nearly 1,000 men whose cancer had not yet been trea…

This early-stage study is checking how two prostate cancer drugs, JNJ-56021927 and abiraterone acetate, interact in the body when taken together. It involves 57 men whose prostate cancer has spread and is no longer responding to standard hormone-blocking treatments. The main goal…

This is an early-stage study to check the safety and how the body processes a new drug called MK-5684 (opevesostat) in Japanese men with advanced prostate cancer. The cancer has spread and no longer responds to standard hormone therapy or chemotherapy. The main goal is to see wha…

This large, late-stage study is testing whether adding the drug apalutamide to standard hormone therapy, given both before and after prostate removal surgery, works better than hormone therapy alone for men with high-risk prostate cancer that hasn't spread. The main goals are to …

This early-stage study is testing the safety and finding the right dose of an experimental drug called JNJ-78278343 for men with advanced prostate cancer that has spread. The drug is designed to redirect the body's own immune T-cells to attack prostate cancer cells. The study wil…

This study is testing if a new type of imaging scan can better detect prostate cancer that has spread to other parts of the body, like bones. Men with metastatic prostate cancer will get two different scans to compare their accuracy. The goal is to see if the new scan, which uses…

This study is testing whether a special type of MRI scan can help doctors better decide which men with low-risk prostate cancer can safely be monitored instead of treated right away. It involves 200 men already enrolled in a monitoring program. The goal is to see if the MRI can s…

This study aimed to see if a 3-month supervised exercise program could improve quality of life and physical fitness for men with advanced prostate cancer. It planned to compare men who received the personal training with those who only got general exercise advice. The trial was w…

This study aims to understand the genetic causes of cancer that run in families. Researchers are collecting blood or saliva samples from patients with certain cancers and their relatives to build a DNA bank. The goal is to identify genetic patterns that increase cancer risk, whic…

This study aims to find better tools to detect prostate cancer cells that may be circulating in the blood. Researchers will test different lab tools (antibodies) on blood samples from 40 men with prostate cancer and 20 healthy men. The goal is to improve future tests that could h…