New Immune-Guiding drug shows promise in advanced prostate cancer trial

NCT ID NCT04898634

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a new drug, JNJ-78278343, that helps the body's immune T-cells find and attack prostate cancer cells. It involves 216 men with advanced prostate cancer that has spread. The main goals are to find the safest and most effective dose and to monitor side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

metastatic prostate carcinoma prostate cancer prostate neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • APHM Hopital Timone

    Marseille, 13005, France

  • Antoni van Leeuwenhoek

    Amsterdam, 1066 CX, Netherlands

  • Centre Leon Berard

    Lyon, 69373, France

  • Chongqing University Cancer Hospital

    Chongqing, 400030, China

  • Columbia University Medical Center Herbert Irving Pavilion

    New York, New York, 10032, United States

  • Erasmus MC

    Rotterdam, 3015 GD, Netherlands

  • First Affiliated Hospital Of Wenzhou Medical College

    Wenzhou, 325399, China

  • Hosp Univ Fund Jimenez Diaz

    Madrid, 28040, Spain

  • Hosp Univ Hm Sanchinarro

    Madrid, 28050, Spain

  • Hosp Virgen de La Victoria

    Málaga, 29010, Spain

  • Institut Gustave Roussy

    Villejuif, 94800, France

  • Memorial Sloan Kettering Cancer Center

    New York, New York, 10065, United States

  • National Cancer Center Hospital East

    Kashiwa, 277 8577, Japan

  • Peking University Third Hospital

    Beijing, 100191, China

  • Sun Yat Sen University Cancer Center

    Guangzhou, 510710, China

  • University of Washington

    Seattle, Washington, 98195-9472, United States

  • Yokohama City University Medical Center

    Yokohama, 232 0024, Japan