PROSTATIC NEOPLASMS
Clinical trials for PROSTATIC NEOPLASMS explained in plain language.
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New drug combo for tough prostate cancer shows early promise, but trial halted
Disease control TerminatedThis early-phase study tested a combination of two oral drugs, abemaciclib and darolutamide, in 10 men with metastatic castration-resistant prostate cancer that had spread despite standard hormone therapy. The main goal was to check safety and side effects. The trial was terminat…
Matched conditions: PROSTATIC NEOPLASMS
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 28, 2026 00:00 UTC
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Promising prostate cancer combo trial halted before results
Disease control TerminatedThis phase 2 trial tested two drugs—cabozantinib and abiraterone—together in 54 men with castration-resistant prostate cancer that had spread to bones. The goal was to see if the combination could delay cancer growth. However, the study was stopped early by the sponsor for busine…
Matched conditions: PROSTATIC NEOPLASMS
Phase: PHASE2 • Sponsor: Exelixis • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Prostate cancer vaccine trial halted early – did it work?
Disease control TerminatedThis study tested a vaccine called PROSTVAC-V/F in 33 men who had their prostate removed due to cancer and were at high risk of the cancer returning. The goal was to see if the vaccine could keep cancer from coming back. The study was stopped early, so results are limited, but it…
Matched conditions: PROSTATIC NEOPLASMS
Phase: PHASE2 • Sponsor: Medical University of South Carolina • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Prostate cancer treatment may change how men process common sleep aid
Knowledge-focused TerminatedThis pilot study looked at how the sleep drug zolpidem (Ambien) is processed in men with prostate cancer before and after they start hormone therapy that lowers testosterone. Researchers compared these results to healthy women, since women are known to have higher drug levels. Th…
Matched conditions: PROSTATIC NEOPLASMS
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Can a video game teach surgeons to remove prostate cancer?
Knowledge-focused TerminatedThis study tested whether an online video simulator helps surgeons learn laparoscopic radical prostatectomy, a surgery for prostate cancer. It enrolled 29 surgeons who were new to the procedure, comparing those who used the simulator to those who did not. The trial was terminated…
Matched conditions: PROSTATIC NEOPLASMS
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Blood marker may predict prostate cancer drug response
Knowledge-focused TerminatedThis study aimed to see if a substance in the blood called uPAR can help predict how well men with advanced prostate cancer respond to the drug abiraterone. Only 3 men were enrolled before the study was stopped early. The goal was to find a simple blood test that could guide trea…
Matched conditions: PROSTATIC NEOPLASMS
Sponsor: Kristoffer Rohrberg • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC