Radioactive antibody takes aim at Hard-to-Treat prostate cancer
NCT ID NCT04644770
First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 30 times
Summary
This early-stage study tests a new drug, JNJ-69086420, which is an antibody carrying a radioactive particle that targets a protein found on prostate cancer cells. The study involves about 144 men with advanced prostate cancer that has spread and no longer responds to hormone therapy. The main goals are to find the safest dose and to see if the drug can shrink tumors or lower PSA levels.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Case Western Reserve University
Cleveland, Ohio, 44106, United States
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City of Hope
Duarte, California, 91010, United States
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East Jefferson General Hospital
Metairie, Louisiana, 70006, United States
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Mayo Clinic Arizona
Phoenix, Arizona, 85054, United States
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Mayo Clinic Rochester
Rochester, Minnesota, 55905, United States
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Mayo Clinic in Florida
Jacksonville, Florida, 32224, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Tulane University Hospital & Clinics
New Orleans, Louisiana, 70112, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Utah Huntsman Cancer Institute
Salt Lake City, Utah, 84112, United States
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XCancer Omaha / Urology Cancer Center
Omaha, Nebraska, 68130, United States
Conditions
Explore the condition pages connected to this study.