PROCEDURAL PAIN

This trial tests whether a robotic pet or a video can reduce pain, fear, and anxiety in children aged 5-10 during a blood draw (venipuncture). Children are randomly assigned to interact with a robotic pet, watch an animal video, or receive routine care during the procedure. Resea…

This trial tests whether using a portable hand fan to speed up alcohol evaporation before an IV insertion reduces pain. Adults aged 18 to 65 who need an IV will have two cannulations—one with standard alcohol prep and one with added fanning—to compare pain scores. The goal is to …

This trial tests whether virtual reality (VR) distraction can reduce pain in children aged 6-11 during intravenous cannulation or blood sampling in a pediatric emergency department. Half of the participants receive standard care, while the other half wear a VR headset showing age…

This trial tests whether watching an entertaining video through virtual reality glasses or on a tablet can reduce pain, anxiety, and fear in children aged 7 to 12 during intravenous (IV) cannulation in an emergency department. Children are randomly assigned to one of three groups…

This study tests two non-drug approaches to help children aged 7–12 feel less pain, fear, and anxiety during a blood draw. One group uses Buzzy®, a device that applies cold and vibration near the needle site. Another group receives a cognitive behavioral package that includes age…

This study tests two simple, non-drug methods to reduce pain and fear in children aged 6-9 during blood draws. One group watches a cartoon, the other squeezes a stress ball. Researchers will measure pain and fear levels during the procedure to see which works better.

This study tests whether showing preschool children a short, AI-generated educational video before common medical procedures (like shots or blood draws) can reduce their anxiety, pain, and negative behavior afterward. About 110 children aged 3 to 6 will either watch the video or …

This study tests whether a ShotBlocker device or a warm gel pack can reduce pain and improve comfort in healthy newborns during routine heel prick blood tests. Babies are randomly assigned to receive one of these two non-drug treatments or standard care. Researchers measure pain …

This study will test whether playing with a rain stick or a musical egg during a blood draw can lower pain, fear, and anxiety in children ages 4 to 6. About 120 children will be randomly assigned to use one of these toys or receive standard care. The goal is to find a simple, non…

This study tested three non-drug methods to reduce pain, fear, and anxiety during subcutaneous injections in 45 children aged 6–12 with cancer. The approaches were Buzzy® (a device that vibrates and cools the skin), a cognitive-behavioral coaching package, and a kaleidoscope for …

This study tested whether listening to music and applying acupressure before needle insertion can reduce pain in dialysis patients. 72 participants were split into four groups: music plus acupressure, acupressure alone, music alone, or standard care. Pain was measured during thre…

This study tested if a social robot could help children aged 4-12 with chronic diseases feel less fear and pain during a blood draw. 90 children were split into three groups: one that played with a robot, one that played a digital game, and one that received standard care. The go…

This study tested whether squeezing a stress ball during an ultrasound-guided biopsy can reduce pain and anxiety. 79 adults were randomly assigned to either use a stress ball or receive standard care alone. Researchers measured pain, anxiety levels, and vital signs before and aft…

This study tested whether listening to an audio book or feeling a local vibration can reduce pain and fear in children aged 4-6 during a routine shot. 120 children in a pediatric emergency unit were randomly assigned to one of these methods or standard care. The goal was to find …

This study compared two numbing creams for pain during skin treatments like laser and microneedling. 63 adults rated their pain after using either a standard 4% lidocaine cream or a stronger mix of three anesthetics. The goal was to see which cream provides better pain relief dur…

This study looked at whether a gentle touch technique can help reduce pain and keep breathing stable in preterm infants during painful procedures in the NICU. Researchers compared 60 babies who received gentle touch with those who got standard care. The goal was to see if this si…

This study tested a realistic breathing toy (a plush dog that moves and sounds like it's breathing) to distract children aged 1-3 during blood draws. Eighty kids were split into two groups: one used the toy, the other got standard care. Results showed the toy group had 51% less p…

This study tested whether giving children aged 4-6 a liquid hourglass or a spiky ball during a blood draw can reduce their pain, fear, and anxiety. 120 children were randomly assigned to use one of the toys or receive standard care. The goal was to see if these simple distraction…

This study tested two simple methods to reduce pain and fear in children aged 6-9 when a peripheral IV is removed. One method involved squeezing a stress ball as a distraction, and the other used an alcohol-free silicone spray to gently remove the adhesive tape. The study include…

This study tested whether watching cartoons (passive distraction) or playing games (active distraction) works better to reduce pain and fear in children aged 6-9 years during a routine IV placement. Sixty-four children took part, and researchers measured their pain and fear using…

This study looked at whether virtual reality glasses or simple game cards can help children aged 5 to 10 feel less fear, anxiety, and pain during wound care. Ninety kids were split into three groups: standard care, care with game cards, or care with virtual reality. Researchers m…