PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Clinical trials for PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS explained in plain language.
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New drug shows promise in slowing progressive MS disability
Disease control CompletedThis study tested an experimental drug called SAR442168 against a placebo in 767 adults with primary progressive multiple sclerosis (PPMS). The goal was to see if the drug could delay worsening disability. Participants took the drug or placebo and were monitored for changes in mo…
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE3 • Sponsor: Sanofi • Aim: Disease control
Last updated May 15, 2026 11:57 UTC
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Cord blood cells injected into spine: hope for MS patients?
Disease control CompletedThis early-phase trial tested the safety of a new cell therapy called DUOC-01, made from donated umbilical cord blood, in 20 adults with primary progressive multiple sclerosis (PPMS). The cells were injected into the spinal fluid. The main goal was to see if the treatment was saf…
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE1 • Sponsor: Joanne Kurtzberg, MD • Aim: Disease control
Last updated May 07, 2026 18:39 UTC
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New analysis digs into ocrelizumab's effect on brain inflammation in progressive MS
Knowledge-focused CompletedThis study re-examines MRI scans from 732 people with primary-progressive multiple sclerosis who took part in the ORATORIO trial. Researchers want to see if ocrelizumab changes a specific brain area called the choroid plexus, which may be linked to inflammation. The goal is to be…
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Sponsor: State University of New York at Buffalo • Aim: Knowledge-focused
Last updated May 17, 2026 02:41 UTC