Cord blood cells injected into spine show promise for MS
NCT ID NCT04943289
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tested a new cell therapy called DUOC-01, made from donated umbilical cord blood, in 20 adults with primary progressive multiple sclerosis (PPMS). The cells were injected into the spinal fluid to see if it was safe. Researchers also looked for early signs of benefit on brain scans and disability scores.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- DUOC-01 (cells from donated umbilical cord blood)
- What this could lead to
- If safe, this could pave the way for a new treatment that slows or repairs nerve damage in progressive MS.
- What could go wrong
- This is a very early, small safety trial with only 20 people. It is not designed to prove effectiveness, and side effects from the injection or cells are possible.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Duke University Medical Center
Durham, North Carolina, 27705, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Cheaper MS drug could match pricey standard in major trial