PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Clinical trials for PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS explained in plain language.
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Monthly MS injection aims to halt disability progression
Disease control TerminatedThis study tested a long-acting form of glatiramer acetate (GA Depot) given as a monthly shot to people with primary progressive multiple sclerosis (PPMS). The goal was to see if it could safely slow down worsening disability. The trial was stopped early, but it involved 30 adult…
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Mapi Pharma Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Melatonin trial for MS halted early – what we know
Disease control TerminatedThis study tested whether adding melatonin to the standard drug ocrelizumab could safely slow disability in people with progressive primary multiple sclerosis. The trial was terminated early, so results are limited. Participants were adults aged 18–65 with this type of MS.
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE1, PHASE2 • Sponsor: Fundación Pública Andaluza para la gestión de la Investigación en Sevilla • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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MS drug trial halted after failing to lower nerve damage
Disease control TerminatedThis study tested an oral drug called SAR443820 in 174 adults with multiple sclerosis (MS) to see if it could lower a marker of nerve damage in the blood. The trial was stopped early because the drug did not meet its main goal of reducing that marker. Participants were followed f…
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: PHASE2 • Sponsor: Sanofi • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Tears may replace spinal taps for MS diagnosis
Diagnosis TerminatedThis study tests whether a tear sample can diagnose primary progressive multiple sclerosis (MS) as accurately as a spinal tap. Currently, doctors need to collect spinal fluid to confirm this type of MS, which is invasive and uncomfortable. Researchers will compare proteins in tea…
Matched conditions: PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS
Phase: NA • Sponsor: Lille Catholic University • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC