New analysis digs into ocrelizumab's effect on brain inflammation in progressive MS

NCT ID NCT05974852

First seen Mar 20, 2026 · Last updated May 15, 2026 · Updated 10 times

Summary

This study re-examines MRI scans from 732 people with primary-progressive multiple sclerosis who took part in the ORATORIO trial. Researchers want to see if ocrelizumab changes a specific brain area called the choroid plexus, which may be linked to inflammation. The goal is to better understand how the drug works, not to test a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PRIMARY PROGRESSIVE MULTIPLE SCLEROSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • Buffalo Neuroimaging Analysis Center

    Buffalo, New York, 14203, United States

Conditions

Explore the condition pages connected to this study.