POSTURAL TACHYCARDIA SYNDROME

This study is testing if a medication called moxonidine can help people with a condition called POTS feel better when they stand up. POTS causes symptoms like a racing heart, dizziness, and fatigue upon standing. Researchers will give moxonidine or a placebo to about 48 adults wi…

This study is testing whether a medication called modafinil can help improve concentration and mental clarity in people with Postural Tachycardia Syndrome (POTS). Researchers are enrolling 20 adults with POTS to compare modafinil against a placebo and another medication. The goal…

This study is testing whether giving an intravenous (IV) infusion of saline (salt water) can improve exercise capacity in people with Postural Tachycardia Syndrome (POTS). Researchers will compare exercise performance on a day when participants receive saline versus a day they re…

This study is testing if a blood pressure medication called moxonidine can reduce symptoms like rapid heartbeat, dizziness, and nausea when standing in people with Postural Tachycardia Syndrome (POTS). Researchers will give the medication to 48 participants with POTS for 4 weeks …

This study is testing whether a special breathing device can help people with Postural Orthostatic Tachycardia Syndrome (POTS) stand up without feeling dizzy or having their heart race. Researchers are enrolling 30 people diagnosed with POTS to see if breathing through the device…

This study aims to find out if some people with Postural Tachycardia Syndrome (POTS) have specific immune proteins that might cause their symptoms. Researchers will measure these proteins in the blood of 58 people with POTS and healthy volunteers to see if they are linked to the …

This study aims to understand how people with chronic dizziness and rapid heartbeat when standing (called orthostatic intolerance or POTS) process salt differently than healthy people. Researchers will compare 30 participants—some with the condition and some healthy controls—by m…

This study aims to understand why people with Postural Tachycardia Syndrome (POTS) experience 'brain fog'—difficulty with thinking and memory. Researchers will use MRI brain scans to compare brain activity in 21 people with POTS to healthy volunteers while they do thinking tests.…

This study aims to understand if people with orthostatic intolerance (a condition causing dizziness upon standing) have worse sleep than healthy people. Researchers will use activity-tracking watches to measure sleep patterns in 100 participants. The goal is to gather information…

This study is screening women with suspected Postural Tachycardia Syndrome (POTS) to understand their condition better. It involves detailed tests to measure blood volume, hormone levels, and nervous system function. The goal is to gather information for future research on whethe…

This study aims to validate a simpler blood test for measuring a protein called NET, which is thought to play a role in Postural Tachycardia Syndrome (POTS). Researchers will compare the new blood test results with older, more complex methods in about 200 people, including those …