POSTURAL TACHYCARDIA SYNDROME

This study looks at whether a simple saltwater infusion can help people with Postural Tachycardia Syndrome (POTS) exercise more easily. Forty adults with POTS will have their exercise ability tested after receiving either saline or a placebo. The goal is to see if the saline impr…

This study looks at whether moxonidine, a drug that lowers sympathetic nerve activity, can reduce symptoms like rapid heartbeat and lightheadedness in people with Postural Tachycardia Syndrome (POTS). About 48 women with POTS will take either the drug or a placebo for 4 weeks. Th…

This study tests whether breathing through a small resistance device can help people with Postural Orthostatic Tachycardia Syndrome (POTS) stand up longer and reduce their rapid heart rate. About 30 adults with POTS will use the device and be monitored. The goal is to see if this…

This study looks at whether people with Postural Orthostatic Tachycardia Syndrome (POTS) have trouble keeping salt in their bodies compared to healthy people. Researchers will measure how much salt comes out in urine and check stress hormone levels. The goal is to better understa…

This study looks at whether a simple blood test can measure how well the body clears a chemical called norepinephrine in people with Postural Tachycardia Syndrome (POTS). POTS causes a rapid heart rate and other symptoms when standing. The test measures a substance called NET mRN…

This study looks at whether people with POTS (a condition causing a rapid heart rate upon standing) have higher levels of certain immune proteins that might attack their own nervous system. Researchers will measure these proteins in blood samples from 58 participants, including b…

This study looks at why people with Postural Tachycardia Syndrome (POTS) experience a rapid heart rate and other symptoms when standing. Researchers will test a drug called Moxonidine, which lowers nerve activity that controls heart rate, to see if it reduces symptoms. The goal i…

This study screens people with suspected Postural Tachycardia Syndrome (POTS) and healthy volunteers to see how their bodies handle salt and regulate blood volume. Researchers measure blood volume and hormone levels after changes in dietary salt. The goal is to learn more about t…

This study looks at whether a single dose of modafinil, a drug that promotes wakefulness, can improve concentration and thinking speed in people with Postural Tachycardia Syndrome (POTS). About 20 adults with POTS will take the drug and then complete computer-based attention and …

This study looks at sleep quality in people with postural tachycardia syndrome (POTS) compared to healthy volunteers. Participants wear an activity watch for several days to track sleep patterns. The goal is to understand if POTS causes sleep disturbances, not to test a treatment…

This study aims to understand why people with Postural Tachycardia Syndrome (POTS) experience 'brain fog'—difficulty with thinking and memory. Researchers will use brain scans to compare brain activity in 21 people with POTS to healthy volunteers while they do thinking tasks. The…

This study looks at whether postural tachycardia syndrome (POTS) is caused by the body's immune system attacking itself. Researchers will test if stimulating the vagus nerve can reduce symptoms and inflammation. The study includes 80 people with POTS and healthy volunteers, but i…