POTS puzzle: is it an autoimmune attack?

NCT ID NCT02725060

First seen Nov 12, 2025 · Last updated May 16, 2026 · Updated 21 times

Summary

This study looks at whether people with POTS (a condition causing a rapid heart rate upon standing) have higher levels of certain immune proteins that might attack their own nervous system. Researchers will measure these proteins in blood samples from 58 participants, including both POTS patients and healthy volunteers, to see if they relate to symptoms and if levels stay stable over time. The goal is to better understand the cause of POTS, not to test a treatment.

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Contacts and locations

Locations

  • Autonomic Dysfunction Center

    Nashville, Tennessee, 37232, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73117-1213, United States

Conditions

Explore the condition pages connected to this study.