POSTTRAUMATIC STRESS DISORDER (PTSD)
Clinical trials for POSTTRAUMATIC STRESS DISORDER (PTSD) explained in plain language.
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Can MDMA-Assisted therapy heal trauma in young adults?
Disease control Not yet recruitingThis study is testing a new approach for young adults (ages 18-26) with posttraumatic stress disorder (PTSD) who have experienced childhood trauma. The treatment combines the substance MDMA with talk therapy sessions, known as MDMA-assisted therapy. The main goals are to see if t…
Matched conditions: POSTTRAUMATIC STRESS DISORDER (PTSD)
Phase: PHASE2 • Sponsor: Jenna M. Traynor • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Ear stimulation may tame both fibromyalgia pain and PTSD
Symptom relief Not yet recruitingThis trial tests whether a wearable device that gently stimulates the vagus nerve through the ear can reduce pain and PTSD symptoms in veterans who have both conditions. Participants receive six sessions of a brief PTSD therapy along with either active or sham stimulation over fo…
Matched conditions: POSTTRAUMATIC STRESS DISORDER (PTSD)
Phase: NA • Sponsor: VA Office of Research and Development • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Can writing about trauma in a group ease PTSD for those with BPD traits?
Symptom relief Not yet recruitingThis study tests whether a 10-week virtual group therapy, where people write about their traumatic experiences, can reduce PTSD symptoms in adults who also have borderline personality disorder (BPD) traits. The therapy is called Group Extended Written Exposure Therapy (GE-WET). R…
Matched conditions: POSTTRAUMATIC STRESS DISORDER (PTSD)
Phase: NA • Sponsor: St. Joseph's Healthcare Hamilton • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Brain zaps tailored to you: new hope for PTSD?
Symptom relief Not yet recruitingThis study tests a personalized form of brain stimulation (PrTMS) for PTSD in 100 military veterans. Unlike standard treatments, it uses an EEG brainwave test to customize the therapy to each person. Participants will receive either active treatment or a sham version over 6 weeks…
Matched conditions: POSTTRAUMATIC STRESS DISORDER (PTSD)
Phase: NA • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:07 UTC
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New study aims to find best talk therapy for traumatized teens with chronic illness
Symptom relief Not yet recruitingThis study will enroll 400 youth aged 8-18 with chronic medical conditions who have experienced trauma. Participants will first receive group therapy using either SPARCS or UP, two evidence-based talk therapies. Those who still need help after group therapy will then receive indi…
Matched conditions: POSTTRAUMATIC STRESS DISORDER (PTSD)
Phase: NA • Sponsor: Anthony Vesco • Aim: Symptom relief
Last updated Jun 27, 2026 11:02 UTC
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Can brain and body clues predict PTSD treatment success in teens?
Knowledge-focused Not yet recruitingThis study examines how 180 adolescents aged 14-18 with trauma-related symptoms react to stress and strong emotions. Researchers will measure brain activity, heart rate, and anxiety while teens repeatedly imagine details of their own traumatic event. The goal is to understand whi…
Matched conditions: POSTTRAUMATIC STRESS DISORDER (PTSD)
Phase: EARLY_PHASE1 • Sponsor: Medical University of South Carolina • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Can magnetic pulses calm the brain in PTSD and depression?
Knowledge-focused Not yet recruitingThis study looks at how two types of noninvasive brain stimulation affect brain activity and the body's stress system in people with both PTSD and major depression. Fifty adults will receive both active and sham stimulation in random order, with brain and heart measurements taken…
Matched conditions: POSTTRAUMATIC STRESS DISORDER (PTSD)
Phase: NA • Sponsor: Tri-Service General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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Patients' voices: which anxiety therapy works best for you?
Knowledge-focused Not yet recruitingThis study interviews 30 adults with generalized anxiety, social anxiety, or PTSD who previously completed a trial comparing two therapies: metacognitive therapy (MCT) and cognitive-behavioral therapy (CBT). The goal is to learn what participants thought about each treatment to h…
Matched conditions: POSTTRAUMATIC STRESS DISORDER (PTSD)
Phase: NA • Sponsor: Karolinska Institutet • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC