PERITONEAL CARCINOMATOSIS
Clinical trials for PERITONEAL CARCINOMATOSIS explained in plain language.
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New drug combo aims to tackle Chemotherapy-Resistant colorectal cancer in the abdomen
Disease control OngoingThis trial investigates whether combining two drugs—galunisertib and capecitabine—can help people with advanced colorectal cancer that has spread to the lining of the abdomen (peritoneal metastases) and no longer responds to standard chemotherapy. The study has two parts: first, …
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: PHASE1, PHASE2 • Sponsor: The Netherlands Cancer Institute • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Chemotherapy sprayed directly into the abdomen: a new attack on stubborn cancers
Disease control OngoingThis phase 1 trial tests a new method of delivering chemotherapy for people with cancers that have spread to the lining of the abdomen (peritoneal carcinomatosis) from gastrointestinal cancers like colorectal, stomach, or pancreatic cancer. The drug, nanoliposomal irinotecan (Oni…
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: PHASE1 • Sponsor: University Hospital, Ghent • Aim: Disease control
Last updated Jul 15, 2026 00:00 UTC
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Heated chemo during surgery shows promise for rare abdominal cancer
Disease control OngoingThis phase 2 trial tests whether giving heated chemotherapy directly into the abdomen during surgery can help people with a rare and aggressive adrenal cancer that has spread within the belly. About 30 participants will have surgery to remove visible tumors, followed by a wash of…
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: PHASE2 • Sponsor: Columbia University • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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New way to deliver chemo for stomach cancer shows promise in early trial
Disease control OngoingThis early-phase trial is testing the safety and best dose of the chemotherapy drug paclitaxel when given directly into the abdomen (intraperitoneal) for people with advanced stomach or gastroesophageal cancer that has spread to the lining of the abdomen. The study involves 27 pa…
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Could chemo around surgery beat cancer spread in the belly?
Disease control OngoingThis study tests whether giving chemotherapy before and after surgery (plus heated chemo directly into the abdomen) helps people with colorectal cancer that has spread to the lining of the abdomen live longer. About 358 adults with resectable disease are randomly assigned to eith…
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: PHASE2, PHASE3 • Sponsor: Koen Rovers • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Experimental cancer combo aims to supercharge immune attack on tumors
Disease control OngoingThis early-phase trial tests an experimental drug called IMP321, which activates immune cells, in combination with other cancer treatments like chemotherapy or immunotherapy. The study includes 83 people with advanced solid tumors, including lung and bladder cancers. The main goa…
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: PHASE1 • Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New combo therapy targets rare abdominal cancer
Disease control TerminatedThis study tests whether adding a special chemotherapy spray (PIPAC) directly into the abdomen to standard IV chemo can help people with a rare cancer of the belly lining (peritoneal mesothelioma) live longer. About 66 adults who have not had prior treatment will be randomly assi…
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: PHASE2 • Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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Stomach cancer trial combines Belly-Infused chemo with standard drugs
Disease control OngoingThis phase II trial tests a combination of chemotherapy drugs for stomach cancer that has spread to the lining of the abdomen. About 40 adults will receive standard intravenous chemo plus paclitaxel infused directly into the abdomen. The goal is to see if this approach improves h…
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: PHASE2 • Sponsor: University of California, Irvine • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Light-Activated therapy shows promise for tumor control without surgery
Knowledge-focused OngoingThis study follows people who have received photodynamic therapy (PDT) for various cancers, including head and neck, lung, and skin tumors. PDT uses a light-sensitive drug and a special light to destroy cancer cells while sparing healthy tissue. Researchers will review medical re…
Matched conditions: PERITONEAL CARCINOMATOSIS
Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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Personalized blood test aims to track stomach and colon cancer spread
Knowledge-focused TerminatedThis study is for people with gastrointestinal cancer that has spread to the lining of the abdomen. Researchers will collect tumor tissue and blood samples to create a custom blood test that looks for cancer DNA. The goal is to see if this test can help doctors monitor the cancer…
Matched conditions: PERITONEAL CARCINOMATOSIS
Phase: NA • Sponsor: Rutgers, The State University of New Jersey • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC