Heated chemo during surgery shows promise for rare abdominal cancer

NCT ID NCT03127774

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether giving heated chemotherapy directly into the abdomen during surgery can help people with a rare and aggressive adrenal cancer that has spread within the belly. About 30 participants will have surgery to remove visible tumors, followed by a wash of heated cisplatin. The main goal is to see how long they live without the cancer coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cisplatin (heated chemotherapy given into the abdomen during surgery)

What this could lead to

If successful, this approach could offer a way to delay cancer recurrence in patients with adrenocortical carcinoma that has spread within the abdomen.

What could go wrong

This is a small, early-phase trial with only 30 participants, so results may not apply to all patients. Heated chemotherapy also carries risks of serious side effects like kidney damage and infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adrenal carcinoma adrenal cortex carcinoma peritoneal carcinomatosis peritoneal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Columbia University Medical Center

    New York, New York, 10032-3729, United States