Heated chemo during surgery shows promise for rare abdominal cancer
NCT ID NCT03127774
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 trial tests whether giving heated chemotherapy directly into the abdomen during surgery can help people with a rare and aggressive adrenal cancer that has spread within the belly. About 30 participants will have surgery to remove visible tumors, followed by a wash of heated cisplatin. The main goal is to see how long they live without the cancer coming back.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Cisplatin (heated chemotherapy given into the abdomen during surgery)
- What this could lead to
- If successful, this approach could offer a way to delay cancer recurrence in patients with adrenocortical carcinoma that has spread within the abdomen.
- What could go wrong
- This is a small, early-phase trial with only 30 participants, so results may not apply to all patients. Heated chemotherapy also carries risks of serious side effects like kidney damage and infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADRENOCORTICAL CARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Columbia University Medical Center
New York, New York, 10032-3729, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can Lab-Grown tumor models predict the best therapy for each patient?
- Liver tumors targeted directly: old pump, new drug
- Triple chemo cocktail aims to clear deadly bowel blockages in advanced stomach cancer
- Chemotherapy sprayed directly into the abdomen: a new attack on stubborn cancers
- New drug combo aims to tackle Chemotherapy-Resistant colorectal cancer in the abdomen
- Light-Activated therapy shows promise for tumor control without surgery