PERIODONTAL BONE LOSS
Clinical trials for PERIODONTAL BONE LOSS explained in plain language.
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Can a 'gentle' gum surgery plus enamel proteins rebuild bone? small study hints at yes.
Disease control CompletedThis study tested whether adding enamel matrix proteins (Emdogain) and a bovine bone graft to a minimally invasive gum surgery (M-MIST) helps heal deep gum defects better than surgery alone. Forty-five adults with at least one deep gum pocket were treated and followed. The main g…
Matched conditions: PERIODONTAL BONE LOSS
Phase: NA • Sponsor: Rungta College of Dental Sciences and Research • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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Gum disease breakthrough? hyaluronic acid gel may rival standard treatment
Disease control CompletedThis study tested whether a hyaluronic acid gel (HyaDent BG) works as well as Emdogain, a standard treatment, for repairing bone defects caused by gum disease. Both were used with a bone graft material during surgery. Seventeen adults with advanced periodontitis took part. The go…
Matched conditions: PERIODONTAL BONE LOSS
Phase: NA • Sponsor: Medical University of Sofia • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Blood clot gel vs tooth protein: which fixes gum bones better?
Disease control CompletedThis study tested two treatments for deep gum bone defects caused by periodontitis: platelet-rich fibrin (PRF), made from the patient's own blood, and enamel matrix derivative (EMD), a protein gel. Twenty-six patients received one of the treatments after surgery, and their gum he…
Matched conditions: PERIODONTAL BONE LOSS
Phase: PHASE4 • Sponsor: Semmelweis University • Aim: Disease control
Last updated Jun 26, 2026 19:19 UTC
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New lab test could take the guesswork out of antibiotic choice for gum disease
Knowledge-focused CompletedThis study tested a new lab method (xCELLigence system) to grow oral biofilms and select the most effective antibiotic for each patient with chronic periodontitis. 64 adults with severe gum disease received standard deep cleaning plus an antibiotic chosen by the new test. The goa…
Matched conditions: PERIODONTAL BONE LOSS
Phase: PHASE4 • Sponsor: University of Valencia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC