PATENT FORAMEN OVALE
Clinical trials for PATENT FORAMEN OVALE explained in plain language.
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Heart hole closer tested to stop strokes and migraines
Disease control Recruiting nowThis study looks at a device called CeraFlex that closes a small hole in the heart (PFO) which can cause strokes or migraines. About 180 people with PFO and related health issues will get the device. Researchers will check if the procedure is safe and works well, and if the hole …
Matched conditions: PATENT FORAMEN OVALE
Sponsor: Lifetech Scientific (Shenzhen) Co., Ltd. • Aim: Disease control
Last updated May 17, 2026 02:35 UTC
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Heart repair or pills? new study targets stroke prevention in seniors
Disease control Recruiting nowThis study tests whether closing a small hole in the heart (called PFO) plus blood thinners is better than blood thinners alone at preventing another stroke in people aged 60 to 80. It also compares different blood thinners to see which works best. About 792 participants who rece…
Matched conditions: PATENT FORAMEN OVALE
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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HALTI trial: could stopping blood thinners after heart repair be safe for young stroke survivors?
Disease control Recruiting nowThis study looks at whether young patients (60 or younger) who had a stroke caused by a hole in the heart (PFO) can safely stop taking blood thinners one year after the hole is closed. The goal is to see if stopping these drugs reduces bleeding risks without increasing the chance…
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: Josep Rodes-Cabau • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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New heart device aims to prevent future strokes in patients with common heart defect
Disease control Recruiting nowThis study tests a new device (P3 Occluder) to close a small hole in the heart called a PFO, which may have caused a stroke in some people. About 15 adults who had a stroke possibly linked to a PFO will get the device and be followed for up to 5 years. The goal is to see if the d…
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: Recross Cardio, Inc. • Aim: Disease control
Last updated May 08, 2026 12:02 UTC
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Heart hole closure may cut stroke risk in seniors – landmark trial underway
Prevention Recruiting nowThis study tests whether closing a common heart defect called PFO (a small hole between the heart's upper chambers) can prevent repeat strokes in people over 60 who have already had a stroke of unknown cause. About 714 older adults will receive either medication alone or medicati…
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: Josep Rodes-Cabau • Aim: Prevention
Last updated May 17, 2026 02:26 UTC
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Heart fix may silence migraines: new study investigates
Symptom relief Recruiting nowThis study looks at whether closing a small hole in the heart (called PFO) can reduce migraine attacks. Researchers will compare 150 adults with both PFO and migraines to those with PFO but no migraines. They will track headache days and brain fluid function before and after the …
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: First Affiliated Hospital Xi'an Jiaotong University • Aim: Symptom relief
Last updated May 11, 2026 20:40 UTC