PATENT FORAMEN OVALE
Clinical trials for PATENT FORAMEN OVALE explained in plain language.
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New device aims to seal heart holes and prevent strokes
Disease control Recruiting nowThis study follows 180 people who receive the CeraFlex PFO Closure System, a device that closes a small hole in the heart called a patent foramen ovale (PFO). The goal is to see how well the device works in everyday medical practice, especially for patients with migraines or stro…
Matched conditions: PATENT FORAMEN OVALE
Sponsor: Lifetech Scientific (Shenzhen) Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Can closing a heart hole stop strokes in seniors? new trial aims to find out
Disease control Recruiting nowThis study tests whether closing a small hole in the heart (called a PFO) plus medication is better than medication alone at preventing repeat strokes in people over 60 who have had a cryptogenic stroke (a stroke with no clear cause). About 714 participants will be randomly assig…
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: Josep Rodes-Cabau • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New trial tests best way to prevent second stroke in older adults with a hole in the heart
Disease control Recruiting nowThis study involves 792 people aged 60-80 who had a stroke linked to a patent foramen ovale (PFO), a small hole in the heart. It compares three approaches: closing the hole with a device plus antiplatelet drugs, taking newer blood thinners (apixaban, dabigatran, or rivaroxaban), …
Matched conditions: PATENT FORAMEN OVALE
Phase: PHASE3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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HALTI trial: could stopping blood thinners after heart repair be safer?
Disease control Recruiting nowThis study looks at whether people aged 60 or younger who had a stroke caused by a hole in the heart (PFO) can safely stop taking blood thinners one year after the hole is closed. The goal is to see if stopping these drugs reduces the risk of bleeding without increasing the chanc…
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: Josep Rodes-Cabau • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New heart device aims to prevent future strokes by closing a common hole
Disease control Recruiting nowThis study tests a new device (P3 Occluder) to close a small hole in the heart called a PFO in people who have had a stroke possibly linked to that hole. About 15 adults aged 18-65 will get the device and be followed for up to 5 years to see if it safely and effectively closes th…
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: Recross Cardio, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:10 UTC
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Heart fix may stop migraines: new trial tests Hole-Closing procedure
Symptom relief Recruiting nowThis study tests whether closing a small hole in the heart (called a PFO) can reduce migraine attacks and improve brain function. Researchers will compare 150 adults with migraines and a PFO who get the closure procedure to those who don't. The goal is to see if the procedure cut…
Matched conditions: PATENT FORAMEN OVALE
Phase: NA • Sponsor: First Affiliated Hospital Xi'an Jiaotong University • Aim: Symptom relief
Last updated Jun 27, 2026 08:11 UTC